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IUPAC name | (1S,2R,8S,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one | Mol. mass | 374.471 g/mol | Synonyms | (6α, 11β)-11,17,21-trihydroxy-6-methyl-pregna-1,4-diene-3,20-dione | Protein binding | 78% | Metabolism | liver primarily, kidney, tissues; CYP450: 3A4 substrate | Half-life | urine; Half-life: 18-26h (biological) | Routes | IV, IM, IV Infusion, Oral, Rectal, Topical |
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Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug. It is marketed in the USA and Canada under the brand names Medrol and Solu-Medrol. It is also available as a generic drug.
It is a variant of prednisolone, methylated at carbon 6 of the B ring.
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