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Triamcinolone

Drug information
Systematic (IUPAC) name
IUPAC name(11β,16α)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
Chemical data
Mol. mass394.434 g/mol
Synonyms{{hidden|Click show to see|(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one}}
Protein binding68%
MetabolismHepatic
Half-life88 minutes
ExcretionFecal and renal
Therapeutic considerations
RoutesOral, topical, IM, intra-articular, intrasynovial

     Home | Drugs | Triamcinolone



Triamcinolone (trade names Aristocort, Kenacort, Tri-Nasal, Triaderm, Azmacort, Trilone, Volon A, Tristoject, and Tricortone) is a long-acting synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream.

Triamcinolone Video

This video illustrate Intravitreal Injection of Triamcinolone Acetonide (IVTA) performed by Dr Suresh K Pandey at Suvi Eye Institute, Kota, India. The procedure of IVTA should be carried out with meticulous aseptic precaution, preferably in the operating room. It is very easily carried out under topical anesthesia. A pre-injection single drop of Povidone-Iodine (5%) solution is applied to the eye followed by thorough cleaning of the eyelashes and application of a lid speculum. 0.5% proparacaine hydrochloride drops are applied topically. Alternatively, one could also apply cotton tip pledgets soaked in lignocaine hydrochloride (4%) to the injection site for a couple of minutes prior to the injection to decrease the discomfort. Preservative free triamcinolone acetonide in a single-use bottle (40 mg/ml, 1ml bottle, Aurocort, Aurolab, Madurai, India), is drawn into a 1-cc tuberculin syringe after cleansing the top of the bottle with an alcohol wipe. A separate 27 or 26 gauge needle is placed onto the syringe, which is then inverted to remove air bubbles. The excess triamcinolone is discarded till 0.1 ml (4 mg) remains in the syringe. The injection site is usually the inferotemporal quadrant to avoid drug deposition in front of the visual axis. The stab is given 3 mm from the limbus (in aphakic and pseudophakic patients) and 3.5 mm from the limbus in phakic patients to ensure against passage of the needle through the vitreous base. The needle is usually not introduced all the <b>...</b>
0.78 min. | 3.4 user rating
www.bms.com My wife got a shot of Kenalog for ALLERGIES! She ends up with this huge permanent dent on her butt cheek. The drug allegedly leaked out into her subcutaneous tissue (fat) and caused it to shrink. How not worth it! A permanent dent and it didn't even help her allergies. She also suffered menstrual irregularities after this. This is happening to a lot of people. See these links: www.medications.com www.askapatient.com this is the manufacturer's website: www.bms.com The reason that I posted this is to bring awareness to the fact that this CAN and DOES happen. It is a common and often unmentioned side effect.
0.83 min. | 4.63 user rating
technique of using triamcinolone (kenalog) to check the outflow through the ahmed valve for the treatment of glaucoma. Uday Devgan MD, Los Angeles, CA, tel 1-800-337-1969. www.DevganEye.com
0.57 min. | 5.0 user rating
submucous fibrosis is treated with injection of triamcinolone acetonide mixed with xylocaine jelly and injections are given intra lesionally first in retromolar trigone area then on cheek and then on palate.
1.38 min. | 5.0 user rating
Follow me on my journey to "cure" eczema. STOP taking hot showers and START taking WARM baths! 1. I use lukewarm baths with either 1 cup of AHAVA sea salt or Bragg's apple cider vinegar. 2. Dove sensitive skin body wash with loofa 3. Pat dry with a towel 4. Put triamcinolone acetonide ointment onto flare ups 5. Put Eucerin original moisturizing cream onto body 6. Wear long shirts and long pants to bed! 7. I hope your skin feels better!
3.13 min. | 5.0 user rating
Vernal keratoconjunctivitis (VKC) is a severe perennial or seasonal form of allergic conjunctivitis predominantly affecting children and young adults. Eighty percent of patients are below 14 years of age and boys are usually more affected at 2:1 ratio. The chief symptoms of this disease include severe itching, photophobia, redness, tearing and tenacious (ropy) discharge. The important clinical signs in conjunctiva include cobblestone papillae in the upper tarsal conjunctiva, limbal conjunctival thickening with gelatinous nodules and Tranta's dots. Corneal involvement can occur in the form of punctuate keratitis, shield ulcer, scarring and pannus formation.4 In majority of children, the disease resolves spontaneously between age 2 and 10 years. Eyes with refractory and frequently recurrent VKC often develop potentially blinding complications like corneal vascularization, corneal opacity or signs of steroid over use. SUPRATARSAL INJECTION: Triamcinolone acetonide 0.5ml (1 ml = 40 mg drug, Preservative Free sloution AUROCORT) was injected in potential space between conjunctiva and Muller's muscle, 1 mm superior to upper edge of tarsus with a 27 gauge needle after proparacaine hydrochloride 0.5 % was instilled into the eye 3 times at an interval of 2 minutes. This produced ballooning of the potential space between the conjunctiva and Muller's muscle. No eye dressing or patching was used after giving the injection. Topical steroid medications were discontinued & patients were <b>...</b>
2.93 min. | 5.0 user rating
www.eyemovies.co.uk Anterior Vitrectomy: Uses of Triamcinolone Phaco 3.5 Complications
1.07 min. | 3.66 user rating
This video is update you all on my journey to natural skincare. I have eczema and I currently use a cream that has a steroid in it and I'm trying to wean myself off of it to a natural product that me and my roommate created. In the upcoming weeks I will be doing more research and adding more components to the moisturizer to eventually replace my current steroidal cream, which is called triamcinolone. So far the moisturizer we made includes pure shea butter, pure aloe vera, extra virgin olive oil and peppermint essential oil. If you have any skin conditions, including eczema and psoriasis this may be helpful information. Thanks for viewing :-) Don't forget to subscribe & rate the video.
3.75 min. | 5.0 user rating
Triamcinolone assissted vitrectomy in PDR with vitreoschisis
5.02 min. | 5.0 user rating
Vitrectomie après marquage de la hyaloïde postérieure par triamcinolone pour schisi maculaire du myope fort
1.93 min. | 5.0 user rating

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Incredibile in Francia positivo a 12 sostanze - La Repubblica Tweet this news
La Repubblica--Ecco l'incredibile lista: 3'HydroxyStanozolol, 16B-HydroxyStanozolol, 4B-HydroxyStanozolol, 4-Méyhylhexaneamine, Prednisone, Prednisolone, Oxandrolone, Epioxandrolone, Tuaminoheptane, -Triamcinolone- Acétonide, 6B-HydroxyMéthan - Date : Sat, 21 Jan 2012 10:58:25 GMT
Novartis reports positive phase III results from gouty arthritis studies - pharmabiz.com Tweet this news
pharmabiz.com---...- with severe gouty arthritis, showing that ACZ885 (canakinumab) provided superior pain relief and reduced the risk of new attacks by up to 68% compared to an injectable steroid (-triamcinolone- acetonide, TA) used to treat gouty arthri - Date : Thu, 26 May 2011 08:40:28 GMT+00:00
The highly accurate anteriolateral portal for injecting the knee. - 7thSpace Interactive (press release) Tweet this news
7thSpace Interactive (press release)--After hydrodissection of the synovial membrane with lidocaine using a mechanical syringe (reciprocating procedure device), 80 mg of -triamcinolone- acetonide was injected into the knee with a 2.0-in (5.1-cm) 21-gauge - Date : Wed, 30 Mar 2011 07:45:45 GMT+00:00
Study: Different medical therapies after cataract extraction yield similar results - OSN SuperSite Tweet this news
OSN SuperSite--In the prospective, randomized, single-masked study, researchers compared IOP differences, degrees of anterior inflammation and macular edema among patients who instilled prednisone 1%, a postoperative injection of -triamcinolone- followed - Date : Tue, 29 Mar 2011 15:09:00 GMT+00:00
Alimera Clears Some of the Muddle on Eye Implant Data but Nervousness Still ... - Seeking Alpha Tweet this news
Seeking Alpha--However, the company also is able to show that the Iluvien patients underwent significantly fewer on-protocol procedures - laser photocoagulation therapy - and off-protocol procedures - Lucentis, Avastin, vitrectomy or intravitreal -triamci - Date : Sun, 06 Feb 2011 10:10:24 GMT+00:00
Intravitreal Triamcinolone Prior to Laser Treatment of Diabetic Macular Edema ... - DG News Tweet this news
DG News--PURPOSE:: To report the 24 months outcomes from a clinical trial of intravitreal -triamcinolone- acetonide (IVTA) plus laser versus laser treatment only in ... - Date : Tue, 18 Jan 2011 18:00:36 GMT+00:00
Special considerations needed for pseudophakic patients with DME - OSN SuperSite Tweet this news
OSN SuperSite--KAANAPALI, Hawaii � Intravitreal -triamcinolone- with prompt focal/grid laser may be equally as effective as ranibizumab in improving visual acuity and ... - Date : Tue, 25 Jan 2011 16:14:12 GMT+00:00
Novel drug delivery devices show promise for treating retinal disorders - OSN SuperSite Tweet this news
OSN SuperSite--Verisome, Icon Bioscience's intravitreal -triamcinolone- delivery system, uses a 30-gauge biodegradable needle with zero-order kinetics and could be ... - Date : Wed, 02 Feb 2011 16:11:00 GMT+00:00
Nasal Steroids for Hay Fever - About - News & Issues Tweet this news
About - News & Issues--There are also a number of brand name nasal steroids, including Nasonex (mometasone), Veramyst (fluticasone furoate), Nasacort AQ (-triamcinolone-), ... - Date : Tue, 01 Feb 2011 05:35:02 GMT+00:00
Study supports ranibizumab, laser for patients with diabetic macular edema - OSN SuperSite Tweet this news
OSN SuperSite---...- either sham with prompt laser, Lucentis (ranibizumab, Genentech) with prompt laser, ranibizumab with deferred laser or -triamcinolone- with prompt laser. ... - Date : Thu, 20 Jan 2011 16:45:42 GMT+00:00

Stomatological preparations (A01)

Caries prophylactic agentsOlaflur * Sodium fluoride * Sodium monofluorophosphate * Stannous fluoride
Anti-infectives and antisepticsAmphotericin B * Benzoxonium chloride * Chlorhexidine * Chlortetracycline * Clotrimazole * Domiphen * Doxycycline * Eugenol * Hexetidine * Hydrogen peroxide * Mepartricin * Metronidazole * Miconazole * Minocycline * Natamycin * Neomycin * Oxyquinoline * Polynoxylin * Sodium perborate * Tetracycline * Tibezonium iodide
Corticosteroids (Glucocorticoids)Dexamethasone * Hydrocortisone * Triamcinolone
OtherAmlexanox * Acetylsalicylic acid * Becaplermin * Benzydamine * Epinephrine/Adrenalone

Decongestants and other nasal preparations (R01)

Topical
Sympathomimetics, plainCyclopentamine * Ephedrine * Phenylephrine * Oxymetazoline * Tetryzoline * Xylometazoline * Naphazoline * Tramazoline * Metizoline * Tuaminoheptane * Fenoxazoline * Tymazoline * Epinephrine
Antiallergic agents,
excluding corticosteroids
Spaglumic acid histamine antagonists (Levocabastine, Antazoline, Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid, Nedocromil, Azelastine, Olopatadine, Lodoxamide)
CorticosteroidsBeclometasone * Prednisolone * Dexamethasone * Flunisolide * Budesonide * Betamethasone * Tixocortol * Fluticasone * Mometasone furoate * Triamcinolone * Ciclesonide
Other nasal preparationsCafaminol * Calcium hexamine thiocyanate * Retinol * Ipratropium bromide * Ritiometan * Mupirocin * Hexamidine * Framycetin * Hyaluronic acid * Eucalyptus oil
Systemic use:
Sympathomimetics
Phenylpropanolamine * Pseudoephedrine * Phenylephrine * Phenylpropylamine |belowstyle=background:MistyRose

Corticosteroids � glucocorticoid/receptor and mineralocorticoid/receptor
(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) (Endogenous in CAPS)

Mineralocorticoids
(3-one, 4-ene,
no FG at 16)
Pregnenedione: ALDOSTERONE * 11-DEOXYCORTICOSTERONE * HALOGENATED AT 9: Fludrocortisone
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)
PregneneCORTISONE
Pregnenedione
(+20-one)
HYDROCORTISONE/CORTISOL# (Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate) * Budesonide * Ciclesonide * Deflazacort * Medrysone * Tixocortol * HALOGENATED AT 6: Cloprednol * HALOGENATED, WITH FG AT 16: Halcinonide
Pregnadiene (+1-ene)Rimexolone * HALOGENATED, WITH FG AT 16: Flunisolide * Triamcinolone * Amcinonide * Fluocinolone acetonide (Fluocinonide)
Pregnadienediol
(+21-hydroxy)
Prednisone (Meprednisone) * HALOGENATED AT 9: Fluorometholone * HALOGENATED, WITH FG AT 16: Fluocortolone (Clocortolone, Diflucortolone, Fluocortin) * Desoximetasone
Pregnadienetriol
(+11-hydroxy)
Prednisolone# (Methylprednisolone, Methylprednisolone aceponate, Prednicarbate, Prednylidene) * Desonide * HALOGENATED: Fluprednisolone (Difluprednate, Fluperolone) * HALOGENATED, WITH FG AT 16: Dexamethasone# * Betamethasone (Clobetasol, Clobetasone, Diflorasone, Halometasone, Ulobetasol) * Beclometasone * Paramethasone * Alclometasone * Fluclorolone * Flumetasone * Fluprednidene
Pregnatriene
(+2-ene)
Cortivazol
AndrosteneHALOGENATED, WITH FG AT 16: Fluticasone (Fluticasone propionate, Fluticasone furoate)
Other/ungroupedHALOGENATED: Loteprednol * HALOGENATED, WITH FG AT 16: Fludroxycortide * Formocortal * Mometasone furoate
Aldosterone antagonists
Spironolactone * Eplerenone * Potassium canrenoate * Canrenone
Synthesis
Trilostane * Carbenoxolone * Aminoglutethimide * Metyrapone |

Drugs for obstructive airway diseases: asthma/COPD (R03)

Adrenergics, inhalants
Short acting &beta;2-agonistsSalbutamol/Levosalbutamol * Fenoterol * Terbutaline * Pirbuterol * Procaterol * Bitolterol * Rimiterol * Carbuterol * Tulobuterol * Reproterol
Long acting &beta;2-agonists (LABA)Arformoterol * Bambuterol * Clenbuterol * Formoterol * Salmeterol Ultra LABA: Indacaterol
otherEpinephrine * Hexoprenaline * Isoprenaline (Isoproterenol) * Orciprenaline (Metaproterenol)
Glucocorticoids
Beclometasone * Budesonide * Ciclesonide * Fluticasone * Mometasone
Anticholinergics/
muscarinic antagonist
Ipratropium * Tiotropium
Mast cell stabilizers
Cromoglicate * Nedocromil
Xanthines
Doxofylline * Theobromine * Theophylline/Aminophylline
Eicosanoid inhibition
Leukotriene antagonistsMontelukast * Pranlukast * Zafirlukast
Lipoxygenase inhibitorZileuton
Thromboxane receptor antagonistsRamatroban * Seratrodast
Combination products
Budesonide/formoterol * Fluticasone/salmeterol * Ipratropium/salbutamol |belowstyle=background:MistyRose



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