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Cortisol

Cortisol
Drug information
Systematic (IUPAC) name
IUPAC name(11β)-​11,​17,​21-​trihydroxypregn-​4-​ene-​3,​20-​dione
Chemical data
Mol. mass362.460
Therapeutic considerations
Pregnancy cat C
Legal status Rx Only (U.S.) (excluding 1-2% strength topical)
RoutesOral tablets, intravenously, topical

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Cortisol (hydrocortisone) is a steroid hormone, or glucocorticoid, produced by the adrenal gland. It is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. It also decreases bone formation. Various synthetic forms of cortisol are used to treat a variety of different diseases.

Cortisol Video

www.hunterkane.com This is brilliant and the best of its kind. It shows what anger can do. 1. The man has central obesity. 2. He can't solve a problem and blames the machine. 3. Vents his anger and damages the machine. 4. There is an independent witness. 5. He hasn't learnt a thing and has damaged his physiology with 1400 toxins which harm him immediately and for the next 6 hours. 7. He is using fight or flight - the jungle behaviour (Our ancestors used this mechanism 250000 years ago as hunter gatherers). It is the basic default mechanism in the least evolved part of our brain. For the next 6 hours he will be secreting Cortisol, the killer stress hormone increasing his BP, Heart disease, diabetes, obesity, cancer risk factors. STRESS is not what is happening to him: it is STRAIN. (Han Selye, the discoverer of Stress, 52 years ago said ' It is not the swimming or the electric shocks that kill the mouse - it is the anticipation)It is our emotional response to the external events that kills us. Even Young's Modulus in Physics says STRAIN = STRESS/ELASTICITY. SO the more supple you are emotionally the less you suffer. (Think of the farmer you stuck to his land in the middle of the M62!) Change your RESPONSE; not the outside. Buddha said 'When you point a finger at someone, three point back at you! Learn Yoga, Meditation, prayer, dance, painting, singing, laughing. It is easier and smarter and convenient to learn HeartMath : www.HeartMath.Org in US and www.HunterKane.Com in <b>...</b>
0.42 min. | 4.63 user rating
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2.27 min. | 4.55 user rating
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4.80 min. | 4.94 user rating
phoenixnutritionals.com (CLICK HERE) Stress has become so commonplace that most of us don't even think about it on a day-to-day basis. Our society encourages more and more stress for greater and greater success but the ravages of prolonged excess stress can change the body chemistry in many ways such as over-producing a hormone called cortisol. Excess cortisol causes many complications in the body over time, one of which is excessive weight gain. Cortisol and weight gain as well as difficulties with weight loss are directly related to excess stress. Stress management can be accomplished in many ways. Meditation, prayer, and other forms of relaxation are often helpful in stress management. The effects of excess stress on the body can be wide ranging. Most existing health challenges are made worse by excess stress. Nutrition can also come to the rescue in helping to physically manage stress. Stress management with nutrition would include the B complex vitamins, especially pantothenic acid. Pantothenic acid directly supports the adrenal glands, helping to prevent their exhaustion. Herbal extracts are also helpful and should be including in any stress supplement formula. Here at The Institute, we have developed a stress supplement that has proven to be of great help to many thousands of people. This formula helps control cortisol levels, aiding in weight loss, this formula has also helped many people reduce or eliminate their dependency on various drugs. The effects of stress <b>...</b>
9.53 min. | 4.44 user rating
www.bodylogicmd.com BodyLogicMD discusses the relation between cortisol, belly fat and hormones. For more information visit www.bodylogicmd.com
3.95 min. | 4.86 user rating
Es una enfermedad que ocurre cuando el cuerpo produce demasiada hormona cortisol. También puede ocurrir si la persona toma demasiado cortisol u otras hormonas esteroides.
8.00 min. | 4.84 user rating
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4.05 min. | 4.94 user rating
Watch acrobatic geckos perform funky moves with their tails: www.newscientist.com See some new rock climbing robots: technology.newscientist.com Find out how paragliders and falcons compare when they glide and take a watch how a hormone called cortisol can affect a squirrel's learning ability.
3.67 min. | 4.88 user rating
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4.97 min. | 4.94 user rating
Cuddy revealed that we can actually change feelings we have about our own status through the physical positions we take with our bodies. Her research participants had higher levels of testosterone and lower levels of cortisol after only two minutes in a "power pose". Cuddy asked if such findings can have wider implications for empowerment training. Original Website : PopTech.org poptech.org Biography : Amy JC Cuddy is a social psychologist poptech.org Video source file : HD Video (.MOV) videos.poptech.org Quicktime Video (.M4V) videos.poptech.org Audio (.MP3) videos.poptech.org All PopTech videos have a Creative Commons license : Attribution-NonCommercial-ShareAlike 3.0 Unported creativecommons.org as mentionned here www.poptech.org
17.42 min. | 4.93 user rating

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Drug may reduce emotional impact of bad memories - Sydney Morning Herald Tweet this news
Sydney Morning Herald--The study's lead author, Marie-France Marin, said the metyrapone drug significantly decreased the levels of -cortisol-, a stress hormone involved in memory recall. Manipulating -cortisol- close to the time of forming new memori - Date : Mon, 06 Jun 2011 14:25:31 GMT+00:00
Redefining Cognition, Can Inhibiting Cortisol Diminish Memories? - Medical News Today Tweet this news
Medical News Today--Before the viewing of the short, saliva samples were collected from the subjects to measure levels of the stress hormone, -cortisol-. Although stress isn't the only reason that -cortisol- is secreted into the bloodstream, it has b - Date : Thu, 02 Jun 2011 09:10:45 GMT+00:00
Posted On Wednesday, April 13, 2011 at 10:00:09 AM - Mumbai Mirror Tweet this news
Mumbai Mirror--Fragmented sleep can cause a lowered metabolism and increased levels of the hormone -Cortisol-, which results in an increased appetite and a decrease in one's ability to burn calories. Myth: Snoring only affects the health of the snore - Date : Tue, 12 Apr 2011 18:56:12 GMT+00:00
Daily pomegranate juice consumption lowered BP - Endocrine Today Tweet this news
Endocrine Today--“Whilst the effects that we found were slight, they do give us an insight into how pomegranate juice and the hormone -cortisol- can alter this system in the human body to give health improvements.” Al-Dujaili and colleagues conducted - Date : Tue, 12 Apr 2011 14:37:18 GMT+00:00
Pomegranate Juice May Lower Blood Pressure - Medical News Today (press release) Tweet this news
Medical News Today (press release)--The ratio of -cortisol- to cortisone in the urine also dropped after a week of pomegranate juice consumption (1.81 ±1.24 to 0.82 ±0.56, p=0.009). -Cortisol- is an active steroid hormone, produced from cholesterol in t - Date : Tue, 12 Apr 2011 00:11:14 GMT+00:00
Chronic stress can impair memory - UPI.com Tweet this news
UPI.com--EDINBURGH, Scotland, April 6 (UPI) -- University of Edinburgh researchers say high levels of the stress hormone -cortisol- in aging mice made them less able to remember how to navigate a maze. Dr. Joyce Yau of the University of Edinburgh's C - Date : Thu, 07 Apr 2011 04:13:35 GMT+00:00
Drop in positive emotions -- rather than jump in negative -- linked to poorer ... - PhysOrg.com Tweet this news
PhysOrg.com--Anthony Ong, assistant professor of human development in the College of Human Ecology, and colleagues report in the March issue of Health Psychology (30:2) that widowed participants showed a relative flattened daily rhythm of salivary -cortis - Date : Tue, 12 Apr 2011 11:56:27 GMT+00:00
Process connecting stress to memory loss allegedly unlocked - HealthJockey.com Tweet this news
HealthJockey.com--The stress hormone -cortisol- now appears linked with memory loss in the aging brain. If researchers from the Medical Research Council are to be believed, then two receptors in aging brains react to -cortisol-. These receptors may be ass - Date : Mon, 11 Apr 2011 07:19:55 GMT+00:00
Musical interaction key to emotion and, perhaps, longevity - San Diego Union Tribune Tweet this news
San Diego Union Tribune--The study showed a much-reduced rise in stress hormones � ACTH and -cortisol- � for the music group. It seems that music mitigates negative experience. Apparently, these changes are a result of how we interact with music, rather t - Date : Tue, 12 Apr 2011 07:06:37 GMT+00:00
How antidepressants spur brain growth - Chemistry World Tweet this news
Chemistry World--Depressed patients are thought to release greater amounts of glucocorticoid stress hormones, such as -cortisol-, which reduce neurogenesis, causing symptoms such as impaired memory and low mood. Previous research has shown that antidepres - Date : Tue, 12 Apr 2011 14:28:26 GMT+00:00

THE DISORDERS OF CORTISOL SECRETION
Regulation : Factors generally increasing cortisol levels
Plasma ACTH
Plasma Cortisol Primary hypercortisolism (Cushing's syndrome) Secondary hypercortisolism (pituitary or ectopic tumor, Cushing's disease, pseudo-Cushing's syndrome)
Secondary hypocortisolism (pituitary tumor, Sheehan's syndrome) Primary hypocortisolism (Addison's disease, Nelson's syndrome)

Endocrine system: hormones (Peptide hormones * Steroid hormones)

Endocrine
glands

Endocrine system: hormones (Peptide hormones * Steroid hormones)

Endocrine
glands
Endocrine
glands
subgroup |Hypothalamic-
pituitary |
Adrenal axis
Adrenal cortex: aldosterone * cortisol * DHEA
Adrenal medulla: epinephrine * norepinephrine
Thyroid axis
Thyroid: thyroid hormone (T3 and T4) * calcitonin
Parathyroid: PTH
Gonadal axis
Testis: testosterone * AMH * inhibin Ovary: estradiol * progesterone * activin and inhibin * relaxin (pregnancy) Placenta: hCG * HPL * estrogen * progesterone
Other end.
glands
Pancreas: glucagon * insulin * somatostatin Pineal gland: melatonin Thymus: Thymosin * Thymopoietin * Thymulin

Corticosteroids � glucocorticoid/receptor and mineralocorticoid/receptor
(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) (Endogenous in CAPS)

Mineralocorticoids
(3-one, 4-ene,
no FG at 16)
Pregnenedione: ALDOSTERONE * 11-DEOXYCORTICOSTERONE * HALOGENATED AT 9: Fludrocortisone
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)
PregneneCORTISONE
Pregnenedione
(+20-one)
HYDROCORTISONE/CORTISOL# (Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate) * Budesonide * Ciclesonide * Deflazacort * Medrysone * Tixocortol * HALOGENATED AT 6: Cloprednol * HALOGENATED, WITH FG AT 16: Halcinonide
Pregnadiene (+1-ene)Rimexolone * HALOGENATED, WITH FG AT 16: Flunisolide * Triamcinolone * Amcinonide * Fluocinolone acetonide (Fluocinonide)
Pregnadienediol
(+21-hydroxy)
Prednisone (Meprednisone) * HALOGENATED AT 9: Fluorometholone * HALOGENATED, WITH FG AT 16: Fluocortolone (Clocortolone, Diflucortolone, Fluocortin) * Desoximetasone
Pregnadienetriol
(+11-hydroxy)
Prednisolone# (Methylprednisolone, Methylprednisolone aceponate, Prednicarbate, Prednylidene) * Desonide * HALOGENATED: Fluprednisolone (Difluprednate, Fluperolone) * HALOGENATED, WITH FG AT 16: Dexamethasone# * Betamethasone (Clobetasol, Clobetasone, Diflorasone, Halometasone, Ulobetasol) * Beclometasone * Paramethasone * Alclometasone * Fluclorolone * Flumetasone * Fluprednidene
Pregnatriene
(+2-ene)
Cortivazol
AndrosteneHALOGENATED, WITH FG AT 16: Fluticasone (Fluticasone propionate, Fluticasone furoate)
Other/ungroupedHALOGENATED: Loteprednol * HALOGENATED, WITH FG AT 16: Fludroxycortide * Formocortal * Mometasone furoate
Aldosterone antagonists
Spironolactone * Eplerenone * Potassium canrenoate * Canrenone
Synthesis
Trilostane * Carbenoxolone * Aminoglutethimide * Metyrapone |

Cholesterol and steroid metabolic intermediates

General
|Mevalonate pathway |
Non-mevalonate pathway
DOXP * MEP * CDP-ME * CDP-MEP * MEcPP * HMB-PP * IPP * DMAPP
To Cholesterol
Farnesyl pyrophosphate * Squalene * 2,3-Oxidosqualene * Lanosterol Lanosterol * Lathosterol * 7-Dehydrocholesterol * Cholesterol Lanosterol * Zymosterol * 7-Dehydrodesmosterol * Desmosterol * Cholesterol
Steroid

Cholesterol and steroid metabolic intermediates

General
|Mevalonate pathway |
Non-mevalonate pathway
DOXP * MEP * CDP-ME * CDP-MEP * MEcPP * HMB-PP * IPP * DMAPP
To Cholesterol
Farnesyl pyrophosphate * Squalene * 2,3-Oxidosqualene * Lanosterol Lanosterol * Lathosterol * 7-Dehydrocholesterol * Cholesterol Lanosterol * Zymosterol * 7-Dehydrodesmosterol * Desmosterol * Cholesterol
Steroid
General
|Mevalonate pathway |
Non-mevalonate pathway
DOXP * MEP * CDP-ME * CDP-MEP * MEcPP * HMB-PP * IPP * DMAPP
To Cholesterol
Farnesyl pyrophosphate * Squalene * 2,3-Oxidosqualene * Lanosterol Lanosterol * Lathosterol * 7-Dehydrocholesterol * Cholesterol Lanosterol * Zymosterol * 7-Dehydrodesmosterol * Desmosterol * Cholesterol
Steroid
subgroup |groupstyle= |liststyle= |Corticosteroids
(C21 pregnane) |
MineralocorticoidsPregnenolone * Progesterone * 11-Deoxycorticosterone * Corticosterone * Aldosterone
GlucocorticoidsPregnenolone * 17-Hydroxypregnenolone * 17-Hydroxyprogesterone * 11-Deoxycortisol * Cortisol
Cortisol * Cortisone
Sex steroids
Androgens
(C19 androstane)
DHEA * Androstenedione/5-Androstenediol * Testosterone * Dihydrotestosterone
DHEA sulfate * Epitestosterone
Estrogens
(C18 estrane)
Estrone * Estradiol * Estriol

Otologicals (S02)

Anti-infectivesAcetic acid * Aluminium acetotartrate * Boric acid * Chloramphenicol * Chlorhexidine * Ciprofloxacin * Clioquinol * Gentamicin * Hydrogen peroxide * Miconazole * Neomycin * Nitrofurazone * Ofloxacin * Polymyxin B * Rifamycin * Tetracycline
CorticosteroidsBetamethasone * Dexamethasone * Fluocinolone acetonide * Hydrocortisone * Prednisolone
Analgesics and anestheticsLidocaine * Cocaine * Phenazone



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