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Betamethasone

Betamethasone
Drug information
Systematic (IUPAC) name
IUPAC name(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro- 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro- 3H-cyclopenta[a]phenanthren-3-one
Chemical data
Mol. mass392.461
Bioavailability?
Metabolismhepatic CYP3A4
Half-life5.6 hours
ExcretionRenal (in urine)
Therapeutic considerations
Legal status Rx-only
Routesoral or topical

     Home | Drugs | Betamethasone





Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone does not cause water retention. It is applied as a topical cream, ointment, foam, lotion or gel to treat itching. Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection (I.M) for itching from various ailments including allergic reactions to poison ivy and similar plants.

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Health alert over herbal appetizer - Oman Daily Observer Tweet this news
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LEO Pharma Inc. Debuts LEO(R) Quality Care Program for Plaque Psoriasis Patients - MarketWatch (press release) Tweet this news
MarketWatch (press release)--Taclonex(R) (calcipotriene 0.005% and -betamethasone- dipropionate 0.064%) Ointment is approved for use on the skin to treat psoriasis vulgaris (plaque psoriasis) in adults 18 years of age and older and should be applied to af - Date : Wed, 11 Jan 2012 15:54:49 GMT
GSK deposits Rs.71cr into DPEA for overcharging betamethasone bulk & formulations - pharmabiz.com Tweet this news
pharmabiz.com--Glaxo India has deposited Rs.71.21 crore into the Drug Price Equalization Account (DPEA) for overcharging -betamethasone- bulk drugs and its formulations. The company's decision to deposit the amount is in compliance with the Supreme C - Date : Wed, 08 Jun 2011 02:35:45 GMT+00:00
Betamethasone for RA Joint Pain - Global Medical News Network Tweet this news
Global Medical News Network--Unguided intra-articular injection of -betamethasone- in small and large peripheral joints in patients with early RA results in rapid, effective, and long-lasting inflammatory control when used with systemic medication, said D - Date : Wed, 08 Jun 2011 21:21:32 GMT+00:00
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pharmabiz.com--This action Does Not affect products manufactured at its PharmaForce Inc. subsidiary, including its -Betamethasone- Sodium Phosphate and -Betamethasone- Sodium Acetate Injectable Suspension, USP. Osteohealth and Regency Therapeutics Divisio - Date : Tue, 26 Apr 2011 08:48:31 GMT+00:00
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Vasoprotectives (C05)

Antihemorrhoidals for topical usecorticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) other (Tribenoside)
Antivaricose therapyheparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) other (Calcium dobesilate)
Capillary stabilising agentsbioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside)

Decongestants and other nasal preparations (R01)

Topical
Sympathomimetics, plainCyclopentamine * Ephedrine * Phenylephrine * Oxymetazoline * Tetryzoline * Xylometazoline * Naphazoline * Tramazoline * Metizoline * Tuaminoheptane * Fenoxazoline * Tymazoline * Epinephrine
Antiallergic agents,
excluding corticosteroids
Spaglumic acid histamine antagonists (Levocabastine, Antazoline, Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid, Nedocromil, Azelastine, Olopatadine, Lodoxamide)
CorticosteroidsBeclometasone * Prednisolone * Dexamethasone * Flunisolide * Budesonide * Betamethasone * Tixocortol * Fluticasone * Mometasone furoate * Triamcinolone * Ciclesonide
Other nasal preparationsCafaminol * Calcium hexamine thiocyanate * Retinol * Ipratropium bromide * Ritiometan * Mupirocin * Hexamidine * Framycetin * Hyaluronic acid * Eucalyptus oil
Systemic use:
Sympathomimetics
Phenylpropanolamine * Pseudoephedrine * Phenylephrine * Phenylpropylamine |belowstyle=background:MistyRose

Drugs for obstructive airway diseases: asthma/COPD (R03)

Adrenergics, inhalants
Short acting &beta;2-agonistsSalbutamol/Levosalbutamol * Fenoterol * Terbutaline * Pirbuterol * Procaterol * Bitolterol * Rimiterol * Carbuterol * Tulobuterol * Reproterol
Long acting &beta;2-agonists (LABA)Arformoterol * Bambuterol * Clenbuterol * Formoterol * Salmeterol Ultra LABA: Indacaterol
otherEpinephrine * Hexoprenaline * Isoprenaline (Isoproterenol) * Orciprenaline (Metaproterenol)
Glucocorticoids
Beclometasone * Budesonide * Ciclesonide * Fluticasone * Mometasone
Anticholinergics/
muscarinic antagonist
Ipratropium * Tiotropium
Mast cell stabilizers
Cromoglicate * Nedocromil
Xanthines
Doxofylline * Theobromine * Theophylline/Aminophylline
Eicosanoid inhibition
Leukotriene antagonistsMontelukast * Pranlukast * Zafirlukast
Lipoxygenase inhibitorZileuton
Thromboxane receptor antagonistsRamatroban * Seratrodast
Combination products
Budesonide/formoterol * Fluticasone/salmeterol * Ipratropium/salbutamol |belowstyle=background:MistyRose

Otologicals (S02)

Anti-infectivesAcetic acid * Aluminium acetotartrate * Boric acid * Chloramphenicol * Chlorhexidine * Ciprofloxacin * Clioquinol * Gentamicin * Hydrogen peroxide * Miconazole * Neomycin * Nitrofurazone * Ofloxacin * Polymyxin B * Rifamycin * Tetracycline
CorticosteroidsBetamethasone * Dexamethasone * Fluocinolone acetonide * Hydrocortisone * Prednisolone
Analgesics and anestheticsLidocaine * Cocaine * Phenazone



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