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Fluocinonide

Fluocinonide
Drug information
Systematic (IUPAC) name
IUPAC name6α,9-difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone,21-acetate
Chemical data
Mol. mass494.525 g/mol
Metabolismhepatic
Therapeutic considerations
Pregnancy cat C
Routestopical

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Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort.

The usual prescription concentration is 0.05% as a topical cream, ointment, or gel. The application area should normally not be covered after application. In certain cases, the physician may recommend the use of an occlusive dressing after application to increase the rate and depth of absorption. The frequency of application depends on the condition being treated and the area affected, but most often it should be applied twice a day.

Fluocinonide ranks as a "high-potency" (second-highest rank) topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects.

Fluocinonide should not be used if infection is present. It should not be applied to the eyes or to sensitive areas such as the genitals or anus.

A common potential adverse effect is skin atrophy (thinning of the skin). Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal axis (HPA) suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in

some patients.

Fluocinonide should be used with caution when treating children, pregnant women, nursing mothers, and anyone using the medication for longer than two weeks.

Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs. Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure.



Fluocinonide Video

Fluocinonide is usually contained in psoriasis and eczema topical solutions. Learn more on www.fluocinonide.org
0.85 min. | 5.0 user rating
Clarification video: www.youtube.com Continuing my journey battling this extreme disease. Documenting improvements since last visit to Univ of Utah at end of March '12. Also, medication changes and treatment changes: - Immunosuppressant: Cyclosporin (continuing) - Reduce bleach in bath to every other day. - Topical ointments: protopic, triamcinolone, desonide, fluocinonide (continuing) - Muciprocin inside ear, nose, and on open wounds on body (continuing) - Stopped Keflex (previously taking 500mg 4x/day for 10 days per month) - Creams: vanicream, CeraVe (continuing) - Bath: Robathol, salt - Gastrocrom - UV Light treatment: sitting in shade outside - Vitamins: Calcium, Vitamin D3
20.17 min. | 0 user rating
Link to post: jeffreylin.net Response to 7/19/12 Health Update: www.youtube.com Clarification for those of you who don't know the severity and complexity of my allergy disease. I list a lot of medications and treatments in my health update videos, but HOW CAREFULLY I use these medications are worth spending time explaining. I'll go out on a limb and say few if any of you will have allergies anywhere as extreme as mine. Therefore, the combinations of all the medications and treatments I use are last resort. This video is in response to a comment left on the last health update video (for 7/19/12 Utah Medical Trip). As the user said, steroids (topical and oral) should be avoided and only used sparingly in times of crisis. I stated in my very first health update video that taking too much prednisone led to the severity of my condition at the time. Steroids thins (and eventually destroys) all skin, leaving you defenseless and worse than you started. If your condition is limited to one or two diagnosis such as just Eczema, just Asthma, or just GI diseases, find the best ways to care for those areas. Do testing to figure out what your immune system is reacting to, and avoid as much as you can. I avoid all food, eating a strictly Elecare diet. It is extremely difficult to stop eating food, but that's how far I need to go. You need the determination to do the same. When you know what's causing the problems, you need to stop any activities that will get you sick, even if its food <b>...</b>
11.87 min. | 0 user rating

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JPMorgan Chase & Co. (JPM) Analysts Reiterate an "Overweight" Rating on ... - LocalizedUSA Tweet this news
LocalizedUSA--Its primary brands are DYSPORT, PERLANE Injectable Gel, RESTYLANE Injectable Gel, SOLODYN, VANOS (-fluocinonide-) Cream 0.1%, and ZIANA (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel. Shares of Medicis Pharmaceutic opened at 33.76 on - Date : Wed, 28 Dec 2011 14:36:10 GMT
Средство от псориаза Лосьон от псориаза Фуфан - Бизнес-справочник "Пульс цен" Tweet this news
Бизнес-справочник "Пульс цен"--Состав: -fluocinonide-, салициловая кислота, камфор, borneolum syntheticun, этанол и др. Описание: жидкость светло коричне - Date : Mon, 02 Jan 2012 15:16:02 GMT
Medicis Pharmaceutic (MRX) Shares Downgraded to a "Hold" Rating by Canaccord ... - LocalizedUSA Tweet this news
LocalizedUSA--Its primary brands are DYSPORT, PERLANE Injectable Gel, RESTYLANE Injectable Gel, SOLODYN, VANOS (-fluocinonide-) Cream 0.1%, and ZIANA (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel. In December 2011, it acquired Graceway Pharmaceuti - Date : Mon, 09 Jan 2012 16:36:11 GMT
จับร้านขายส่งเครื่องสำอางเถื่อน มูลค่า 2 ล้านบาท - ไทยรัฐ Tweet this news
ไทยรัฐ---...- ขวัญข้าว เนเจอร์+โบท็อกซ์ โกลด์ ผสมคอลลาเจน (Kwun Kouw Nature+Botox Gold ผสม Collagen) รวมทั้ง ยังพบยาอันตร - Date : Mon, 30 May 2011 10:39:13 GMT+00:00
FDA approves Taro's Canadian pharmaceutical facility - Globes Tweet this news
Globes--The inspection at the Brampton facility related to flaws in the production of an anti-itch and acne cream -Fluocinonide- and for ringworm cream Cicloopirox Olamine. Taro interim CEO James Kedrowski said, We have worked diligently at the Brampton f - Date : Tue, 26 Apr 2011 12:17:07 GMT+00:00
Dinkes Depok Sita Ratusan Butir Obat dari Apotek Ilegal - Okezone Tweet this news
Okezone--"Contohnya kalau obat ilegal yakni -Fluocinonide-, kalau kosmetik ilegal seperti DR Cream, Lean Hua, dan cream 99," jelasnya kepada okezone, Rabu (30/03/11). Yulia menambahkan, obat-obatan tersebut disita dan akan dikembalikan k - Date : Wed, 30 Mar 2011 17:22:58 GMT+00:00
BBPOM Surabaya Temukan 19.376 Produk Ilegal dan Berbahaya - Suarasurabaya.net Tweet this news
Suarasurabaya.net--Beberapa merek obat, kosmetik ataupun pangan yang harus diwaspadai antara lain super stud 007, -fluocinonide- cream, dragee hijau tanpa kabel, samsu super cream, huangdi shengdan jiaonang, nangen zengzhangsu luquan, jamu galian becak ta - Date : Mon, 14 Feb 2011 10:15:14 GMT+00:00

Corticosteroids � glucocorticoid/receptor and mineralocorticoid/receptor
(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) (Endogenous in CAPS)

Mineralocorticoids
(3-one, 4-ene,
no FG at 16)
Pregnenedione: ALDOSTERONE * 11-DEOXYCORTICOSTERONE * HALOGENATED AT 9: Fludrocortisone
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)
PregneneCORTISONE
Pregnenedione
(+20-one)
HYDROCORTISONE/CORTISOL# (Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate) * Budesonide * Ciclesonide * Deflazacort * Medrysone * Tixocortol * HALOGENATED AT 6: Cloprednol * HALOGENATED, WITH FG AT 16: Halcinonide
Pregnadiene (+1-ene)Rimexolone * HALOGENATED, WITH FG AT 16: Flunisolide * Triamcinolone * Amcinonide * Fluocinolone acetonide (Fluocinonide)
Pregnadienediol
(+21-hydroxy)
Prednisone (Meprednisone) * HALOGENATED AT 9: Fluorometholone * HALOGENATED, WITH FG AT 16: Fluocortolone (Clocortolone, Diflucortolone, Fluocortin) * Desoximetasone
Pregnadienetriol
(+11-hydroxy)
Prednisolone# (Methylprednisolone, Methylprednisolone aceponate, Prednicarbate, Prednylidene) * Desonide * HALOGENATED: Fluprednisolone (Difluprednate, Fluperolone) * HALOGENATED, WITH FG AT 16: Dexamethasone# * Betamethasone (Clobetasol, Clobetasone, Diflorasone, Halometasone, Ulobetasol) * Beclometasone * Paramethasone * Alclometasone * Fluclorolone * Flumetasone * Fluprednidene
Pregnatriene
(+2-ene)
Cortivazol
AndrosteneHALOGENATED, WITH FG AT 16: Fluticasone (Fluticasone propionate, Fluticasone furoate)
Other/ungroupedHALOGENATED: Loteprednol * HALOGENATED, WITH FG AT 16: Fludroxycortide * Formocortal * Mometasone furoate
Aldosterone antagonists
Spironolactone * Eplerenone * Potassium canrenoate * Canrenone
Synthesis
Trilostane * Carbenoxolone * Aminoglutethimide * Metyrapone |

Vasoprotectives (C05)

Antihemorrhoidals for topical usecorticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) other (Tribenoside)
Antivaricose therapyheparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) other (Calcium dobesilate)
Capillary stabilising agentsbioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside)



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