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Canrenone

Drug information

Systematic (IUPAC) name
IUPAC name	10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Chemical data
Mol. mass	340.456 g/mol
Protein binding	85 - 90%

Home | Drugs | Canrenone

Canrenone is an aldosterone antagonist.

The active form, and first metabolite of, Spironolactone.

Canrenone Video

A positive drugs test normally marks the end of an athlete's Olympic dream. But USA goalkeeper Hope Solo will be allowed to take her place at London 2012. The 30-year old tested positive for Canrenone last month but its position as a specified substance means Solo only receives a public warning. 'Specified substances' are those which are more susceptible to credible non-doping explanations. She says the substance came from a prescribed medication and acted in accordance with the US Anti-Doping Agency. Solo is aiming for a second successive gold medal, after backstopping the team to success in 2008. Bookmark: www.youtube.com Subscribe - www.youtube.com Twitter - twitter.com Facebook Goal UK: www.facebook.com Goal International: www.facebook.com

0.77 min. | 2.16 user rating

Like us on Facebook: www.facebook.com Follow us on Twitter: twitter.com Olympic gold medalist Hope Solo tested positive for banned substance after providing a urine sample that tested positive for Canrenone, which is not a PED, but works as a diuretic, and is sometimes used to flush the system, causing it to be banned by the USADA. Solo claims she was taking the medication in a "therapeutic dose under the care of a physician." The soccer star has accepted the warning and will still play for the United States in the Olympic tournament.

1.07 min. | 3.0 user rating

US national team goalkeeper Hope Solo received a public warning Monday from the US Anti-Doping Agency after she tested positive for the banned substance Canrenone in a urine test. Solo has accepted the warning and will still play for the United States in the Olympic tournament. The 30-year-old Solo tested positive for Canrenone in a test on June 15.

0.55 min. | 2.0 user rating

Like us on Facebook: www.facebook.com Follow us on Twitter: twitter.com USA Soccer star Hope Solo recently dealt with a drug scandal as she was tested positive for using canrenone. The player was issued a public warning by the US Anti-Doping Agency.Hope responded with a statement to USADA as it was not a situation of an athlete taking performance enhancing drugs to be better than the competition. Will this scandal hurt her image?

1.25 min. | 0 user rating

Baseball Prospectus' Stephani Bee explains the use of diuretics for PMS vs. steroids and why the positive test is no big deal for the US WNT's goalkeeper.

7.97 min. | 3.66 user rating

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Antihypertensives: diuretics (C03)

Sulfonamides (except EA)

CA inhibitors (at PT)		Acetazolamide
Loop (Na-K-Cl at AL)		Furosemide^# * Bumetanide * Torasemide * Etacrynic acid
Thiazides (Na-Cl at DCT, Calcium-sparing)		Hydrochlorothiazide^# * Bendroflumethiazide * Hydroflumethiazide * Chlorothiazide * Polythiazide * Trichlormethiazide * Cyclopenthiazide * Methyclothiazide * Cyclothiazide * Mebutizide
Thiazide-likes (primarily DCT)		Quinethazone * Clopamide * Chlortalidone * Mefruside * Clofenamide * Metolazone * Meticrane * Xipamide * Indapamide * Clorexolone * Fenquizone
Potassium-sparing (at CD)

ESC blockers		Amiloride^# * Triamterene * Benzamil
Aldosterone antagonists		Spironolactone^# * Eplerenone * Potassium canrenoate * Canrenone
Osmotic diuretics (PT, DL)
Mannitol^# * Urea
VAs (DCT and CD)
vaptans: Conivaptan * Mozavaptan * Satavaptan * Tolvaptan tetracyclines: Demeclocycline
Other
mercurial diuretic (Mersalyl) * Theobromine * Cicletanine

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