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Oxetacaine

Oxetacaine
Drug information
Systematic (IUPAC) name
IUPAC name2,2'-(2-hydroxyethylimino)bis [N-(1,1-dimethyl-2- phenylethyl)-N-methylacetamide]
Chemical data
Mol. mass467.643 g/mol
Half-life1 hour
Therapeutic considerations
RoutesOral, topical

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Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan and Brazil, but not the United States; oxetacaine was withdrawn from the UK market in 2002.

Unlike most local anesthetics, oxetacaine is active even in strongly acidic conditions.

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Anesthetics: Local anesthetics - primarily sodium channel blockers (N01B)

Esters
Esters of aminobenzoic acidAmylocaine * Benzocaine * Butacaine * Butamben * Chloroprocaine * Dimethocaine * Meprylcaine * Metabutoxycaine * Orthocaine * Propoxycaine * Procaine (Novocaine) * Proxymetacaine * Risocaine * Tetracaine
Esters of benzoic acid3-(p-Fluorobenzoyloxy)tropane * Cocaine * Cyclomethycaine * Hexylcaine * Piperocaine
Amides
Articaine * Bupivacaine # /Levobupivacaine/Ropivacaine * Carticaine * Cinchocaine * Etidocaine * Lidocaine # * Mepivacaine * Prilocaine * Trimecaine |Combinations |Iontocaine * Lidocaine/prilocaine |belowstyle=background: LemonChiffon
Combinations
Iontocaine * Lidocaine/prilocaine |belowstyle=background: LemonChiffon

Vasoprotectives (C05)

Antihemorrhoidals for topical usecorticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) other (Tribenoside)
Antivaricose therapyheparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) other (Calcium dobesilate)
Capillary stabilising agentsbioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside)



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