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Benzocaine

Benzocaine
Drug information
Systematic (IUPAC) name
IUPAC nameethyl p-aminobenzoate
Chemical data
Mol. mass165.189 g/mol
Therapeutic considerations
RoutesTopical

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Benzocaine is a local anesthetic commonly used as a topical pain reliever, or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments (e.g., products for oral ulcers of Anbesol by Pfizer, Kank-a by Blistex, and Orabase B and Orajel by Church & Dwight). It is also combined with antipyrine to form A/B Otic Drops, (Brand name Auralgan) to relieve earpain and remove earwax.

Benzocaine Video

Ethyl aminobenzoate,(benzocaine), is derived from para aminobenzoic acid,(PABA), by way of a Fischer esterfication reaction involving the reflux of ethanol with an acid catalyst. The ester formed, an amine salt of benzocaine, is converted to benzocaine by the addition of NaOH. The reaction consists of 3 grams PABA, 20ml ethanol, and 3ml sulfuric acid refluxed for 82-90 min, conversion of the amine salt with NaOH, and then washed and filtered with distilled water. Ethyl aminobenzoate or "benzocaine", is a topical anesthetic used in over the counter medicines. Thanks to Ameera Patel for the research and lab procedure.
7.92 min. | 4.93 user rating		 This video demonstrates a 1 year old male patient who developed methemoglobinemia after benzocaine containing gel was applied to his gums for teething.
3.20 min. | 4.46 user rating		 FDA recently issued a Public Health Advisory to remind health care professionals that the overuse of benzocaine anesthetic sprays can cause methemoglobinemia, a potentially life-threatening condition that can result in cyanosis, confusion, hemodynamic instability and coma. Benzocaine sprays, including those sold under the brand names Hurricaine, Topex and Cetacaine, are used to anesthetize the mucous membranes of the mouth and throat when preparing patients for minor surgery, endoscopic procedures and endotracheal intubation. Methemoglobinemia is a known side-effect when benzocaine sprays are used, but the risk can increase when practitioners use multiple sprays or sprays of longer duration than recommended. FDA is reviewing the safety data for these products to determine if additional action is needed. FDA recommends the following actions to help minimize the risk: • Use only the minimum amount of benzocaine spray to produce the required anesthetic effect. • Carefully observe patients treated with benzocaine sprays for signs of methemoglobinemia. These include headache, lightheadedness, shortness of breath, anxiety, fatigue, pale, gray or blue colored skin, and tachycardia. Blood that's chocolate-brown in color is a late sign of life- threatening levels of methemoglobinemia. • Promptly treat patients suspected of having high levels of methemoglobin. Supplemental oxygen alone is not effective. The only known treatment is intravenous administration of methylene blue. • Do <b>...</b>
2.67 min. | 5.0 user rating		 www.fixyourpremature.info How Do Benzocaine Condoms Work?
3.57 min. | 4.99 user rating		 www.chem.missouri.edu AswinGarimalla, Fifth year Graduate Teaching/Research Assistant made these videos and posted them in Youtube for the benefit of Organic Lab undergraduate students under the advise of Prof.Michael Harmata , with the help of Anne Kroeger , lab Assistant.
8.70 min. | 3.76 user rating
Creams, gels and ointments containing topical anesthetics such as lidocaine, tetracaine, benzocaine and prilocaine can be valuable in relieving or preventing pain. But they can be dangerous when used by patients without medical supervision. FDA is aware of two instances in which young women applied these preparations before laser hair removal. They wrapped the affected areas in plastic wrap to increase the numbing effect. Both women experienced seizures, became comatose and died. FDA has other reports of serious side effects from these anesthetic skin preparations, including cardiac arrhythmias, coma, and respiratory failure. If patients are considering medical or cosmetic skin procedures, advise them to consult a healthcare professional about whether a topical anesthetic is needed and, if so, how it can be safely used. Here are some recommendations for patients to consider: • First, patients should be advised to use a topical anesthetic approved by FDA. These can be found by searching for its name or active ingredient in FDA's Electronic Orange Book of Approved Drug Products. If it is not there, it may not be approved. • Patients should use a topical product that contains the lowest concentration of anesthetic drug that will satisfactorily relieve pain. They should apply as little of the product as possible, for the shortest possible time. • Patients should get instructions from a healthcare professional on how to safely use the product, particularly if there will not be <b>...</b>
2.22 min. | 3.66 user rating		 www.ejactraining.com Benzocaine Condoms - How The Most Common Delay Condom Works Benzocaine condoms have become quite popular in the last 5 years or so. They contain a small amount of medical grade anesthetic in the tip that melts into the glans of your penis and allows you to last longer in the bedroom. You can get rid of the condom or use more benzocaine by collecting it from the each one and then you can use as little or as much as you wish. This is similar to using a delay spray such as Stud 100. If you want these condoms then there are two main brands which should be easy to find. The first is the Durex Performa and the other is Trojan Extended Pleasure. Benzocaine condoms are not a permanent cure at all but they can help give you a quick confidence boost which will help you towards your ultimate goal which is to have 100% confidence in the bedroom and 0% fear or anxiety. When and only when this happens, you will be able to go for as long as you want and will be permanently cured. How You Can Last 10-30 Minutes Longer In Bed Tonight Just By Following These 3 Simple Steps: www.ejactraining.com
4.82 min. | 5.0 user rating		 novacaine benzocaine procaine and lidocaine are all available to buy on ebay with world wide delivery ! seller: pleasebuymeplease
3.50 min. | 4.0 user rating		 www.ejactraining.com End Premature Ejaculation Now - 4 premature ejaculation tips. Apologises for the poor video quality! The first tip is to use a delay condom. These contain benzocaine anesthetic and will not cure you completely but can help you to increase your confidence and get closer to that permanent cure. The second tip is kegels. This is where you work out your PC muscle and then use it to stop your ejaculation at the point of no return. Your arousal will remain high and if you do this repeatedly then you can achieve what is known as the MMO, the multiple male orgasm. The third tip is delay sprays. These are like delay condoms but minus the latex condom and being able to use as little or as much anesthetic as you want. The final tip is to try natural training and enjoying the act purely in the moment without thinking about the future or the past. This is the way to get rid of your anxiety and increase your confidence. How You Can Last 10-30 Minutes Longer In Bed Tonight & Permanently End The Pain & Embarrassment Of Premature Ejaculation www.ejactraining.com
5.30 min. | 3.0 user rating		 www.ejactraining.com Premature Ejaculation Stories - My Own Personal Journey To Overcoming Premature Ejaculation I talk about my own personal premature ejaculation story in this video. I have had anxiety problems for a while and this is not uncommon with PE sufferers. This is significant because the true, underlying cause of premature ejaculation is anxiety in the bedroom. I tried a number of things such as delay sprays like stud 100 and benzocaine delay condoms but they did not cure me. I finally saw the bigger picture about intercourse, it is not about just me but more about sharing and giving and enjoying the unison of man and woman. Also, be a man! Don't worry about being the dominant partner. That is who you are and the way you are built. Don't apologise for being a man! Enjoy being the man, enjoying this mindset and getting the radical increase to your confidence that you need. How You Can Last 10-30 Minutes Longer In Bed Tonight Just By Following These 3 Simple Steps www.ejactraining.com
7.08 min. | 5.0 user rating

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ANE's Day 2 Sees More Than 80 Exhibitors - AVN News (press release) Tweet this news
AVN News (press release)--Company official Guy noted the Deluxion supplements are a topical delay cream that contains no lidocaine of -benzocaine-, but does feature a pantent-pending blend of ingredients. The Zloa Honey is a consumable that claims to give - Date : Thu, 19 Jan 2012 23:04:32 GMT
Bizarro advertising: Durex uses sports to sell sex - The Cheap Seats Tweet this news
The Cheap Seats--To help condom brand Durex sell it's model that contains -Benzocaine-, which is said to help "control climax and prolong" the experience, they used the extra time clocks used in soccer games to demonstrate the effec - Date : Mon, 28 Mar 2011 14:18:48 GMT+00:00
Six years' jail for Inverlochy dealer - Lochaber News Tweet this news
Lochaber News--A search was conducted at MacLean's home and a bag containing three kilograms of -benzocaine-, commonly used to bulk out cocaine, was discovered. Defence counsel John McLaughlin said MacLean had been working as a £600-a-week joiner in - Date : Thu, 31 Mar 2011 16:11:38 GMT+00:00
A 29-YEAR-OLD drug dealer rigged his Widford home with CCTV and captured a ... - This is Total Essex Tweet this news
This is Total Essex--They allegedly found 20.5 grams of cocaine, worth £2240, but they also found 4.98 kilos of -benzocaine- in a kitchen drawer. This is typically used as a cutting agent for cocaine, and could have lowered the purity of the drug out eno - Date : Fri, 11 Mar 2011 08:18:40 GMT+00:00
How to Last Longer in Bed - hitched Tweet this news
hitched--Many of these include a -benzocaine- base (a local anesthetic) that can slow down the level of arousal for a man, but still allow him to feel pleasurable sensations. For a third option, you may want to try using a C-ring (constriction ring), ... - Date : Mon, 28 Mar 2011 16:22:04 GMT+00:00
A SELF-STYLED vigilante has lifted the lid on Borough Green's secret drugs ... - thisiskent.co.uk Tweet this news
thisiskent.co.uk---...- was still there when police raided his home in February 2009. Perrin was found guilty of possessing 20.5g of the class A drug -benzocaine-, worth £1241 and capable of producing more than £250000 of cocaine. Sentencing was adjourn - Date : Wed, 30 Mar 2011 07:10:38 GMT+00:00
H&F drugs cartel busted at Gatwick as police seize BMW, cash and cocaine agent - Fulham Chronicle Tweet this news
Fulham Chronicle--Officers seized £2000 in cash and 25kg of -Benzocaine-, a cutting agent used in the the adulteration of cocaine, and later stormed a house, finding £30000 in cash and a BMW, believed to be worth £35000, which has also been confiscated - Date : Fri, 18 Mar 2011 13:28:43 GMT+00:00
Petrol to be 'watered down' - The Spoof (satire) Tweet this news
The Spoof (satire)--They are mixing it with -Benzocaine- and lidocaine which mimic the numbing effects of cocaine. Just by sight you are not going to know what the quality of the ... - Date : Sun, 16 Jan 2011 09:05:31 GMT+00:00
Hatton man jailed after police raid uncovers drugs - Warwick Courier Tweet this news
Warwick Courier--When the police raided Joseph Steele's home they also found enough -Benzocaine- powder to cut cocaine into street deals worth up to £17600. ... - Date : Sun, 16 Jan 2011 15:52:59 GMT+00:00
Crossbow was found in Accrington drugs raid - The Bolton News Tweet this news
The Bolton News--Miss Worsley said a tin containing a carrier bag with 45 grams of -benzocaine-- a cutting agent - was discovered in a bedroom as well as a further jar of the ... - Date : Sat, 08 Jan 2011 18:50:36 GMT+00:00

Vasoprotectives (C05)

Antihemorrhoidals for topical usecorticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) other (Tribenoside)
Antivaricose therapyheparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) other (Calcium dobesilate)
Capillary stabilising agentsbioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside)

Antipruritics (D04)

Antihistamines for topical useThonzylamine - Mepyramine - Thenalidine - Tripelennamine - Chloropyramine - Promethazine - Tolpropamine - Dimetindene - Clemastine - Bamipine - Isothipendyl - Diphenhydramine - Chlorphenoxamine
Anesthetics for topical useLidocaine - Cinchocaine - Oxybuprocaine - Benzocaine - Quinisocaine - Tetracaine - Pramocaine

Anesthetics: Local anesthetics - primarily sodium channel blockers (N01B)

Esters
Esters of aminobenzoic acidAmylocaine * Benzocaine * Butacaine * Butamben * Chloroprocaine * Dimethocaine * Meprylcaine * Metabutoxycaine * Orthocaine * Propoxycaine * Procaine (Novocaine) * Proxymetacaine * Risocaine * Tetracaine
Esters of benzoic acid3-(p-Fluorobenzoyloxy)tropane * Cocaine * Cyclomethycaine * Hexylcaine * Piperocaine
Amides
Articaine * Bupivacaine # /Levobupivacaine/Ropivacaine * Carticaine * Cinchocaine * Etidocaine * Lidocaine # * Mepivacaine * Prilocaine * Trimecaine |Combinations |Iontocaine * Lidocaine/prilocaine |belowstyle=background: LemonChiffon
Combinations
Iontocaine * Lidocaine/prilocaine |belowstyle=background: LemonChiffon

Throat preparations (R02)

AntisepticsAcriflavinium chloride * Ambazone * Benzalkonium * Benzethonium * Cetrimonium (bromide/chloride) * Cetylpyridinium * Chlorhexidine * Chlorquinaldol * Dequalinium * Dichlorobenzyl alcohol * Hexamidine * Hexylresorcinol * Myristyl-benzalkonium * Oxyquinoline * Phenol * Povidone-iodine
AntibioticsBacitracin * Fusafungine * Gramicidin * Neomycin * Tyrothricin
Local anestheticsBenzocaine * Cocaine * Dyclonine * Lidocaine
OtherFlurbiprofen



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