AskBiography Logo   Latest News  Follow Us on Twitter  Follow Us on Google Buzz  Became Fan - Facebook  Subscribe to RSSRSS   Bookmark and Share

Nabilone

Nabilone
Drug information
Drug nameNabilone
Systematic (IUPAC) name
IUPAC name(6aR,10aR)-rel-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)- -7,8,10,10a-tetrahydro-6H-benzo[c]chromen-9(6aH)-one
Chemical data
Mol. mass372.541 g/mol
Bioavailability20% after first-pass by the liver
Protein bindingsimilar to THC (+/-97%)
Half-life2 hours, with metabolites around 35 hours.
Therapeutic considerations
Pregnancy cat NA
RoutesOral form (PO)- capsule

     Home | Drugs | Nabilone



Nabilone is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain. It is a synthetic cannabinoid, which mimics the main ingredient of cannabis (THC). Chemically, nabilone is similar to the active ingredient found in naturally occurring Cannabis sativa L.

In Canada, the United States, the United Kingdom and Mexico, nabilone is marketed as Cesamet. It was approved in 1985 by the U.S. Food and Drug Administration (FDA) for treatment of chemotherapy-induced nausea and vomiting that has not responded to conventional antiemetics. Though it was approved by the FDA in 1985, the drug only began marketing in the United States in 2006. It is also approved for use in treatment of anorexia and weight loss in patients with AIDS.

Although it doesn't have the official indication (except in Mexico), nabilone is widely used as an adjunct therapy for chronic pain management. Numerous trials and case studies have demonstrated various benefits for condition such as fibromyalgia and multiple sclerosis.

Nabilone is a racemic mixture consisting of the (S,S) and the (R,R) isomers ("trans").

Nabilone Video


5.47 min. | 5.0 user rating
This is how Nabilone works. Kind of.... Assignment for 3rd year Veterinary Pharmacology.
3.80 min. | 3.66 user rating
Amsterdoom - Nabilone Fever from the album Baby In A Bong released june 2011.
5.03 min. | 5.0 user rating
Get those medical secrets: http://www.health101.pw/Medical-Secrets.shtml This video shows you how to say or pronounce Nabilone. Audio is from cancer.gov.
0.13 min. | 5.0 user rating
I'm in Vicious pain and Cramping and can just about move again today.. ....but ... ....It's All in your Mind!!!.. ....my huisarts (Dutch GP) says as he (Patr...
0.72 min. | 0 user rating
This video shows you how to say Nabilone. How would you pronounce Nabilone?
0.12 min. | 0 user rating

Latest News : Nabilone : Tweet this RSS

Want to Nabilone latest news on your twitter account???   sign in with twitter
Nabilone     sign in with twitter   ||  Drugs     sign in with twitter   ||  Health     sign in with twitter
Syria protesters show new strength | Philadelphia Inquirer | 2011-05-14 - Philadelphia Inquirer Tweet this news
Philadelphia Inquirer--In the village of Kafr -Nabil, one- video showed onlookers tossing rose petals upon protesters marching through. The regime's repression has alarmed an international community seeking to support pro-democracy movements inspired - Date : Sat, 14 May 2011 07:14:06 GMT+00:00
Building a Stage for Mideast Peace Before the Final Curtain - New York Times Tweet this news
New York Times--“Juliano was always joking with me, saying, '-Nabil, one- day I'll be shot in the head in the street and I'll shout to you for help,' ” said Nabil al-Raee, 32, the director of the theater's acting school. “Bu - Date : Thu, 07 Apr 2011 00:19:24 GMT+00:00
Mom wants to honour son who saved her life - Winnipeg Free Press Tweet this news
Winnipeg Free Press--She takes -nabilone-, a synthetic derivative of marijuana, to control her nausea, pain and digestive issues. Atienza's pharmacy had just delivered a refill. She took two pills and settled in on the couch with Colby. They were wat - Date : Tue, 29 Mar 2011 08:18:05 GMT+00:00
Woman fined for marijuana 'pills' - Sarnia Observer Tweet this news
Sarnia Observer--She had scissors in her purse, along with two -Nabilone- pills and 15 grams of marijuana. A joint recommendation from Crown and defence lawyers called for a $400 fine given the woman's limited income. Justice Deborah Austin imposed t - Date : Sat, 26 Mar 2011 00:32:33 GMT+00:00
Corruption must be fought from top to bottom: Shoaib - GroundReport Tweet this news
GroundReport--Jammu , March 20 (Scoop News) - While showing serious concern over the abrupt increase in the menace of corruption in Jammu & Kashmir President Pradesh Youth Congress Shaoib -Nabi Lone- has said that it is the ... - Date : Sun, 20 Mar 2011 10:51:22 GMT+00:00
Panel to examine Rent Control Act - GreaterKashmir.com (press release) Tweet this news
GreaterKashmir.com (press release)--The beneficiaries (posthumously) include Mushtaq Ahmed Lone, Mirza Safadar Ali, Ghulam -Nabi Lone- (all former Ministers of State), Muhammad Yousaf Parray alias Kuka Parray, Mir Mustafa and SM Mansoor (all former MLAs). - Date : Thu, 31 Mar 2011 18:49:26 GMT+00:00
Detainee misses KAS exam - GreaterKashmir.com (press release) Tweet this news
GreaterKashmir.com (press release)--Bukhari, who is one of the accused in former minister education Ghulam -Nabi Lone's- murder case, missed his paper after the invigilator did not allow him to enter the exam hall, Bukhari's counsel advocate Mir - Date : Fri, 11 Mar 2011 18:51:53 GMT+00:00
Refractory CRPS Patients Discontinue Opiates With Cannabinoid Treatment - Pain Medicine News (registration) Tweet this news
Pain Medicine News (registration)--“What's notable here is that even with high doses of -nabilone- of up to 10 mg/d, patients experienced few adverse events. Although these first reports show doses of this magnitude are safe, clinicians should alwa - Date : Tue, 29 Mar 2011 04:01:03 GMT+00:00
CIC visits Repository - GreaterKashmir.com (press release) Tweet this news
GreaterKashmir.com (press release)--“An official also pointed out that none of the ministers, except Late Ghulam -Nabi Lone-, (then minister of state for health in PDP-led coalition government) has ever paid a visit to the Kashmir Repository,” they sa - Date : Wed, 16 Mar 2011 19:24:52 GMT+00:00
News Briefs - Peterborough Examiner Tweet this news
Peterborough Examiner--A prescription bottle containing 21 one-milligram pills of Cesamet (the trade name for the drug -nabilone-) and some loose change was stolen from a vehicle in ... - Date : Thu, 13 Jan 2011 11:11:54 GMT+00:00

Antiemetics (A04)

5-HT3 AntagonistsAlosetron * Azasetron * Bemesetron * Cilansetron * Clozapine * Dazopride * Dolasetron * Granisetron * Lerisetron * Metoclopramide * Mianserin * Mirtazapine * Olanzapine * Ondansetron * Palonosetron * Ramosetron * Ricasetron * Tropisetron * Zatosetron
CB1 Agonists (Cannabinoids)Dronabinol * Nabilone * Nonabine
D2/D3 AntagonistsAlizapride * Bromopride * Chlorpromazine * Clebopride * Domperidone * Haloperidol * Itopride * Metoclopramide * Metopimazine * Prochlorperazine * Thiethylperazine
H1 Antagonists (Antihistamines)Cyclizine * Dimenhydrinate * Diphenhydramine * Meclizine * Promethazine
mACh Antagonists (Anticholinergics)Atropine * Hyoscyamine * Scopolamine
NK1 AntagonistsAprepitant * Casopitant * Ezlopitant * Fosaprepitant * Maropitant * Vestipitant
OthersCerium Oxalate * Dexamethasone * Lorazepam * Midazolam * Propofol * Trimethobenzamide

Cannabinoids

Plant cannabinoids
CBCV * CBD * CBDV * CBGM * CBGV * CBN * CBG * CBV * CBL * THC * THC-C4 * THCV |
Cannabinoid metabolites
8,11-DiOH-THC * 11-COOH-THC * 11-OH-THC |
Endogenous cannabinoids
Arachidonoyl ethanolamide (Anandamide or AEA) * 2-Arachidonoylglycerol (2-AG) * 2-Arachidonyl glyceryl ether (noladin ether) * Virodhamine * Palmitoylethanolamide (PEA) * N-Arachidonoyl dopamine (NADA) * Oleamide * RVD-Hpα |
Synthetic cannabinoid
receptor agonists
Classical cannabinoids
(Dibenzopyrans)
A-40174 * A-41988 * A-42574 * Ajulemic acid * AM-087 * AM-411 * AM-855 * AM-905 * AM-906 * AM-919 * AM-938 * AM-4030 * AMG-1 * AMG-3 * AMG-36 * AMG-41 * Dexanabinol (HU-211) * DMHP * Dronabinol * HHC * HU-210 * HU-243 * JWH-051 * JWH-133 * JWH-139 * JWH-229 * JWH-359 * L-759,633 * L-759,656 * Levonantradol (CP 50,5561) * Nabazenil * Nabidrox (Canbisol) * Nabilone * Nabitan * Naboctate * O-806 * O-823 * O-1057 * O-1125 * O-1238 * O-2545 * O-2694 * Parahexyl * Perrottetinene * Pirnabine * THC-O-acetate * THC-O-phosphate
Nonclassical cannabinoids CP 47,497 * CP 55,244 * CP 55,940 * HU-308 * Nonabine * SPA-229 * Tinabinol * 2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene
Benzoylindoles AM-630 * AM-694 * AM-1241 * GW-405,833 (L-768,242) * Pravadoline
Naphthoylindoles AM-1220 * JWH-007 * JWH-015 * JWH-018 * JWH-019 * JWH-073 * JWH-081 * JWH-122 * JWH-182 * JWH-200 * JWH-210 * JWH-398 * WIN 55,212-2
Phenylacetylindoles JWH-203 * JWH-250 * JWH-251 * JWH-302
Naphthoylpyrroles JWH-030 * JWH-147 * JWH-307
Eicosanoids AM-883 * Arachidonyl-2'-chloroethylamide * Arachidonylcyclopropylamide * Methanandamide * O-585 * O-689 * O-1812 * O-1860 * O-1861
Others A-836,339 * Abnormal cannabidiol * BAY 38-7271 * BAY 59-3074 * CB-13 * GW-842,166X * JWH-171 * O-1918 * O-2220 * Leelamine * Org 28611 * VSN-16
Endocannabinoid
activity enhancers
AM-404 * CAY-10401 * CAY-10402 * JZL184 * N-arachidonoyl-serotonin * O-1624 * PF-622 * PF-750 * PF-3845 * URB-597 * URB-602 * Genistein * Arvanil * Olvanil * Kaempferol * Biochanin A * URB-754 |
Cannabinoid receptor
antagonists and
inverse agonists
AM-251 * AM-281 * AM-630 * BML-190 * CAY-10508 * CB-25 * CB-52 * Drinabant * Hemopressin * Ibipinabant * JTE-907 * LY-320,135 * MK-9470 * NESS-0327 * O-1184 * O-1248 * O-2050 * O-2654 * Org 27569 * Otenabant * Rimonabant * SR-144,528 * Surinabant * Taranabant * VCHSR |



Privacy | Sitemap | Micra Hosting