AM-411 : Ask Biography

Drug information

Systematic (IUPAC) name

IUPAC name

(6aR,10aR)-3-(1-adamantyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol

Chemical data

Mol. mass

378.546 g/mol

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AM-411 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC substituted with an adamantyl group at the 3-position, demonstrating that the binding pocket for the alkyl chain at this position can accommodate significant bulk.

AM-411 is a potent and fairly selective CB₁ full agonist with a K_i of 6.80nM, but is still also a moderately potent CB₂ agonist with a K_i of 52.0nM. It produces similar effects to other cannabinoid agonists such as analgesia, sedation, and anxiolysis.

4.30 min. \| 4.95 user rating	60.20 min. \| 4.82 user rating	4.52 min. \| 5.0 user rating	5.48 min. \| 4.97 user rating	5.85 min. \| 4.88 user rating
4.72 min. \| 4.82 user rating	50.02 min. \| 4.70 user rating	86.92 min. \| 4.57 user rating	39.02 min. \| 4.95 user rating	6.53 min. \| 4.72 user rating

AM-411

Home | Drugs | AM-411

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