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HU-210

HU-210
Drug information
Systematic (IUPAC) name
IUPAC name(6aR,10aR)- 9-(Hydroxymethyl)- 6,6-dimethyl- 3-(2-methyloctan-2-yl)- 6a,7,10,10a-tetrahydrobenzo [c]chromen- 1-ol
Chemical data
Mol. mass386.567 g/mol
Synonyms1,1-Dimethylheptyl- 11-hydroxy- tetrahydrocannabinol
Therapeutic considerations
Legal status Schedule I Controlled Substance in the USA

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HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-Myrtenol by the group led by Professor Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 is the ( � )-1,1-dimethylheptyl analog of 11-hydroxy- Δ8- tetrahydrocannabinol, in some references it is called 1,1-dimethylheptyl- 11-hydroxytetrahydrocannabinol. The abbreviation HU stands for Hebrew University.

The (+) enantiomer of HU-210 has almost all of the cannabinoid activity, with the (-) enantiomer HU-211 being inactive as a cannabinoid but instead acts as an NMDA antagonist having neuroprotective effects.

Per a 2005 article in the Journal of Clinical Investigation, HU-210 promotes proliferation, but not differentiation, of cultured embryonic hippocampal NS/PCs likely via a sequential activation of CB1 receptors, G(i/o) proteins, and ERK signaling. It was also indicated by this increased neural growth to entail antianxiety and antidepressant effects.

HU-210, alongside other synthetic cannabinoids like WIN 55,212-2 and JWH-133, is implicated in preventing the inflammation caused by Amyloid beta proteins involved in Alzheimer's Disease, in addition to preventing cognitive impairment and loss of neuronal markers. This anti-inflammatory action is induced through the activation of cannabinoid receptors which prevents microglial activation that elicits the inflammation. Additionally, cannabinoids completely abolish neurotoxicity related to microglia activation in rat models.

HU-210 is a potent analgesic with many of the same effects as natural THC.

HU-210 Video

Scie à ruban HU 210 CSO En vente sur: http://www.cpmo.fr/fr/
0.45 min. | 0 user rating
Scie à ruban HU 210 CSO sous tension en vente sur : http://www.cpmo.fr/fr/
2.33 min. | 0 user rating

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Texas A&M, NCAA work together to root out drug use - Bryan College Station Eagle Tweet this news
Bryan College Station Eagle--Wickerham said that synthetic marijuana involves blends of exotic herbs and plants that are coated with synthetic cannabinoids like cannabicyclohexanol, JWH-018, JWH-073 or -HU-210-, which give the user a marijuana-like high. - Date : Sun, 18 Mar 2012 11:05:22 GMT
Guam Police Seize Over 300 Packages of Spice from Playboy Gift Shop in Harmon - Pacific News Center Tweet this news
Pacific News Center--These chemical compounds typically include -HU-210-, HU-211, JWH-018, and JWH-073. The compund is commonly found in head shops, tobacco shops, various retail outlets and over the Internet and is often marketed as incense or " - Date : Mon, 23 May 2011 21:14:08 GMT+00:00
Agilent Technologies Publishes Industry's First Compendium to Test for ... - VAdvert Press Center (press release) Tweet this news
VAdvert Press Center (press release)--The DEA currently controls six versions of synthetic cannabinoids: JWH-018, JWH-073, JWH-200, CP-47-497 (C7), CP-47-497 (C8) and -HU-210-. There are more than 20 uncontrolled forms, and this number is expected to grow - Date : Tue, 31 May 2011 12:33:18 GMT+00:00
Virginia � Title 18.2 - CRIMES AND OFFENSES GENERALLY. � Chapter 7 - Crimes ... - Leagle.com Tweet this news
Leagle.com---...- mixture, or substance containing, or mixed or infused with, any detectable amount of one or more of the following: (6aR,10aR)-9-(hydroxymethyl)-6, 6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol (other name: - Date : Sat, 02 Apr 2011 10:27:32 GMT+00:00
So-called herbal alternatives are risky, need regulation - UNM Daily Lobo Tweet this news
UNM Daily Lobo--In the United States, synthetic cannabinoid -HU-210- is listed as a Schedule II drug, along with cocaine and codeine. However, other synthetic cannabinoids (JWH 073) remain unscheduled but are “drugs of interest,” according to the Drug - Date : Mon, 28 Feb 2011 07:22:57 GMT+00:00
Heart Month & Congenital Defect Awareness Week highlight new cardiac treatments - Examiner.com Tweet this news
Examiner.com--Similarly, -HU210- has a proven safety profile in humans and given it's favorable myocardial protection properties should be tested in humans. ... - Date : Sun, 30 Jan 2011 23:11:20 GMT+00:00
Der „War on Smarts“ in Polen - Hanf Journal Tweet this news
Hanf Journal--Mephedron wurde dann zusammen mit ein paar JWHs und -HU-210- (künstliche Cannabinoide) verboten. All das hat den Verkauf nicht gestoppt, neue, ... - Date : Thu, 13 Jan 2011 13:43:43 GMT+00:00
Police Warn of Dangerous Unregulated Drugs - KSAL Tweet this news
KSAL--Current Kansas law only outlaws the compounds known as JWH-018, JWH-073, -HU-210- and the stimulants BZP and TFMPP. Very little is known about the ... - Date : Thu, 23 Dec 2010 12:55:53 GMT+00:00
Marine Corps' New Order Bans 'Designer' Drugs - War On Terror News Tweet this news
War On Terror News--One synthetic cannabinoid, -HU-210-, was detected in the substances Spice Gold, Yucatan Fire and Genie. -HU- 210- is controlled under the DEA Controlled ... - Date : Wed, 22 Dec 2010 01:11:37 GMT+00:00
Synthetische Cannabinoide: Lava Red ist das nächste Spice - Online Presseportal Tweet this news
Online Presseportal---...- JWH-018, -HU-210-), allesamt Moleküle, deren Wirkungen auf den menschlichen Körper wenig erforscht sind. Eine Überprüfung des Inhaltes erbrachte zudem, ... - Date : Mon, 13 Dec 2010 07:21:09 GMT+00:00

Cannabinoids

Plant cannabinoids
CBCV * CBD * CBDV * CBGM * CBGV * CBN * CBG * CBV * CBL * THC * THC-C4 * THCV |
Cannabinoid metabolites
8,11-DiOH-THC * 11-COOH-THC * 11-OH-THC |
Endogenous cannabinoids
Arachidonoyl ethanolamide (Anandamide or AEA) * 2-Arachidonoylglycerol (2-AG) * 2-Arachidonyl glyceryl ether (noladin ether) * Virodhamine * Palmitoylethanolamide (PEA) * N-Arachidonoyl dopamine (NADA) * Oleamide * RVD-Hpα |
Synthetic cannabinoid
receptor agonists
Classical cannabinoids
(Dibenzopyrans)
A-40174 * A-41988 * A-42574 * Ajulemic acid * AM-087 * AM-411 * AM-855 * AM-905 * AM-906 * AM-919 * AM-938 * AM-4030 * AMG-1 * AMG-3 * AMG-36 * AMG-41 * Dexanabinol (HU-211) * DMHP * Dronabinol * HHC * HU-210 * HU-243 * JWH-051 * JWH-133 * JWH-139 * JWH-229 * JWH-359 * L-759,633 * L-759,656 * Levonantradol (CP 50,5561) * Nabazenil * Nabidrox (Canbisol) * Nabilone * Nabitan * Naboctate * O-806 * O-823 * O-1057 * O-1125 * O-1238 * O-2545 * O-2694 * Parahexyl * Perrottetinene * Pirnabine * THC-O-acetate * THC-O-phosphate
Nonclassical cannabinoids CP 47,497 * CP 55,244 * CP 55,940 * HU-308 * Nonabine * SPA-229 * Tinabinol * 2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene
Benzoylindoles AM-630 * AM-694 * AM-1241 * GW-405,833 (L-768,242) * Pravadoline
Naphthoylindoles AM-1220 * JWH-007 * JWH-015 * JWH-018 * JWH-019 * JWH-073 * JWH-081 * JWH-122 * JWH-182 * JWH-200 * JWH-210 * JWH-398 * WIN 55,212-2
Phenylacetylindoles JWH-203 * JWH-250 * JWH-251 * JWH-302
Naphthoylpyrroles JWH-030 * JWH-147 * JWH-307
Eicosanoids AM-883 * Arachidonyl-2'-chloroethylamide * Arachidonylcyclopropylamide * Methanandamide * O-585 * O-689 * O-1812 * O-1860 * O-1861
Others A-836,339 * Abnormal cannabidiol * BAY 38-7271 * BAY 59-3074 * CB-13 * GW-842,166X * JWH-171 * O-1918 * O-2220 * Leelamine * Org 28611 * VSN-16
Endocannabinoid
activity enhancers
AM-404 * CAY-10401 * CAY-10402 * JZL184 * N-arachidonoyl-serotonin * O-1624 * PF-622 * PF-750 * PF-3845 * URB-597 * URB-602 * Genistein * Arvanil * Olvanil * Kaempferol * Biochanin A * URB-754 |
Cannabinoid receptor
antagonists and
inverse agonists
AM-251 * AM-281 * AM-630 * BML-190 * CAY-10508 * CB-25 * CB-52 * Drinabant * Hemopressin * Ibipinabant * JTE-907 * LY-320,135 * MK-9470 * NESS-0327 * O-1184 * O-1248 * O-2050 * O-2654 * Org 27569 * Otenabant * Rimonabant * SR-144,528 * Surinabant * Taranabant * VCHSR |



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