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AMG-36

Drug information

Systematic (IUPAC) name
IUPAC name	(6aR,10aR)-3-(1-hexylcyclopentyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
Chemical data
Mol. mass	396.604 g/mol

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AMG-36 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC substituted with a cyclopentane group on the 3-position side chain. AMG-36 is a potent agonist at both CB₁ and CB₂ with moderate selectivity for CB₁, with a K_i of 0.4nM at CB₁ vs 1.9nM at CB₂.

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11.35 min. \| 4.86 user rating	3.78 min. \| 3.83 user rating	3.10 min. \| 2.78 user rating	0.97 min. \| 3.63 user rating	0.32 min. \| 4.78 user rating
6.22 min. \| 4.65 user rating	3.62 min. \| 4.29 user rating	0.63 min. \| 4.64 user rating	7.92 min. \| 3.68 user rating	0.27 min. \| 3.66 user rating

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11.35 min. \| 4.86 user rating	3.78 min. \| 3.83 user rating	3.10 min. \| 2.78 user rating	0.97 min. \| 3.63 user rating	0.32 min. \| 4.78 user rating
6.22 min. \| 4.65 user rating	3.62 min. \| 4.29 user rating	0.63 min. \| 4.64 user rating	7.92 min. \| 3.68 user rating	0.27 min. \| 3.66 user rating