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Azithromycin

Azithromycin
Drug information
Systematic (IUPAC) name
IUPAC name(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo- 11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-]oxy}-1-oxa-6-azacyclopentadec-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside
Chemical data
Mol. mass748.984 g·mol−1
Synonyms9-deoxy-9a-aza-9a-methyl-9a-homoerythromycin A
Bioavailability38% for 250 mg capsules
MetabolismHepatic
Half-life68 hours
ExcretionBiliary, renal (4.5%)
Therapeutic considerations
RoutesOral (capsule or suspension), intravenous, ophthalmic

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Azithromycin is an azalide, a subclass of macrolide antibiotics.

Azithromycin is one of the world's best-selling antibiotics, sold in the United States under the name Zithromax, and under a variety of brand names and generic labels worldwide. It is derived from erythromycin; however, it differs in chemical structure from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring, thus making the lactone ring 15-membered.

Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear infections, tonsillitis, throat infections, laryngitis, bronchitis, pneumonia, Typhoid, and sinusitis. In recent years, it has been used primarily to prevent bacterial infections in infants and those with weaker immune systems. It is also effective against certain venereal diseases, such as non-gonococcal urethritis, chlamydia, gonorrhea, and cervicitis. Recent studies have also indicated it to be effective against late-onset asthma, but these findings are controversial and not widely accepted.

Azithromycin Video

UPDATE: This is not strep, After getting the results back from the lab, it is confirmed that this is NOT strep throat. My luck.. =( Its a nasty viral infection Its been 4 days and I feel like a vampire. Only went out once to give paper work to my job. The monster in my throat is still the same size and thankfully my fever is still down under 100. I want to thank my Family and beautiful girlfriend that has stuck with me through all this. =) OLD NEWS: Strep throat sucks first of all, for the last 3 days I have been in bed sleeping and shaking from a fever of 103. After Motrin every 4 hours I am also taking Azithromycin tablets to help with all. Some cervical neck pain also came along with the dizziness. After looking in the mirror I was shocked to see this thing in my throat.. Be warned now.. its not pretty! errrr time for more sleep.
1.05 min. | 4.31 user rating		 Zithromax (Azithromycin) is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. In children, it is used to treat middle ear infection, pneumonia, tonsillitis, and strep throat. Buy online on www.popularpillsonline.net today!
10.02 min. | 5.0 user rating		 Zithromax is used for treating mild to moderate infections caused by certain bacteria. It may also be used alone or with other medicines to treat or prevent certain infections in persons with advanced HIV infection. It may also be used for other conditions as determined by your doctor. www.24-health.com
3.27 min. | 5.0 user rating		 Zithromax is used for treating mild to moderate infections caused by certain bacteria. It may also be used alone or with other medicines to treat or prevent certain infections in persons with advanced HIV infection. It may also be used for other conditions as determined by your doctor. www.24-health.com
5.42 min. | 3.0 user rating		 also see my Lyme disease blog: freeideasblog.blogspot.com
1.35 min. | 0 user rating
Chronic fatigue syndrome CFS post-viral fatigue syndrome PVFS myalgic encephalomyelitis ME Azithromycin www.translational-medicine.com en.wikipedia.org Background CFS is a clinical state with defined symptoms, but undefined cause. The patients may show a chronic state of immune activation and treatment with an antibiotic in this subgroup has been suggested. Methods In a retrospective study, the response of CFS patients to azithromycin, an antibiotic and immunomodulating drug, has been scored from the patients records and compared with clinical and laboratory data. Azithromycin was not the first choice therapy, but offered when the effect of counseling and L-carnitine was considered insufficient by the patient and the clinician. Results Of the 99 patients investigated, 58 reported a decrease in the symptoms by the use of azithromycin. These responding patients had lower levels of plasma acetylcarnitine. Conclusion The efficacy of azithromycin in the responsive patients could be explained by the modulating effect on a chronic primed state of the immune cells of the brain, or the activated peripheral immune system. Their lower acetylcarnitine levels may reflect a decreased antioxidant defense and/or an increased consumption of acetylcarnitine caused by oxidative stress
2.58 min. | 3.0 user rating		 Azithromycin (Zithromax) is an anti bacterial medicine belonging to a class of medicines known as macrolide antibiotics.
1.28 min. | 0 user rating		 From Kansas City According to a report presented at the Pediatric Academic Societies meeting, an increasing amount of newborns are overweight. Researchers reviewed over 74000 births, finding that as the BMI of pregnant mothers increased significantly from 1990 to 2005, so too did the ponderal index increase in newborns. From New York Treatment of children with cystic fibrosis with azithromycin does not appear to improve lung function, accord to a report published in the Journal of the American Medical Association. Researchers studied over 320 children with cystic fibrosis, randomizing participants to either azithromyzin or placebo. Results showed that the antibiotic group did experience less cough, but did not however experience improved lung function. And finally, from Ghana Vitamin A supplementation does not affect pregnancy related mortality, according to a report published in The Lancet. Researchers studied over 100000 women of reproductive age, randomizing participants to once weekly vitamin A supplementation or placebo. They found that supplementation did not reduce maternal mortality or survival of the children.
1.53 min. | 0 user rating		 Can i drink alcohol while taking Azithromycin - link to online store 6drugs.com Generic Zithromax (Azithromycin) 500mg / 250mg / 100mg Azithromycin is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world's best-selling antibiotics. The highest quality of Azithromycin - Zithromax can i drink alcohol while taking azithromycin
0.58 min. | 0 user rating		 USES Azithromycin is an antibiotic (macrolide-type) used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (eg, common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. HOW TO USE Take this medication by mouth with or without food, usually once a day, or as directed by your doctor. You may take this medication with food if stomach upset occurs. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at the same time each day. Continue to take this medication until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Antacids may decrease the absorption of azithromycin. If you take an antacid, wait at least 2 hours after taking this medication. Inform your doctor if your condition persists or worsens. www.canadadrugcenter.com
0.52 min. | 0 user rating

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Merck Acquiring Inspire Pharmaceuticals - Eye Doc News Tweet this news
Eye Doc News--Merck announced earlier this week that it will be acquiring Inspire Pharmaceuticals, which manufactures ophthalmic treatments such as AZASITE (-azithromycin- ophthalmic solution) 1% for the treatment of bacterial conjunctivitis, and ELESTAT - Date : Thu, 07 Apr 2011 16:42:58 GMT+00:00
Guantanamo in the World Health Day - Solvisión Tweet this news
Solvisión--According to Dr. Esperanza Salazar, head of the Provincial Department of Pharmacoepidemiology in Guantanamo the unnecessary intake of antibiotics such as amoxicillin and -azithromycin- for reasons of convenience or without proper medical presc - Date : Thu, 07 Apr 2011 15:56:24 GMT+00:00
Kerala Medical Services Corpn blacklists 3 cos for violations of tender ... - pharmabiz.com Tweet this news
pharmabiz.com--The company was awarded supply contracts for tablets ciprofloxacin 500 mg, -azithromycin- 250 mg, -azithromycin- 500 mg and fluconazole 150 mg as the eligible lowest bidder for 2010-2011. Based on the tender, the company had executed an agr - Date : Thu, 07 Apr 2011 02:47:20 GMT+00:00
BUYINS.NET: Market Maker Surveillance Report. XLE, XLK, INTC, ISPH, RRD, SNY ... - TMC Net Tweet this news
TMC Net--The company offers AzaSite, an -azithromycin- ophthalmic solution and topical anti-infective for the treatment of bacterial conjunctivitis; Elestat, an epinastine HCl ophthalmic solution and topical antihistamine for the prevention of ocular itch - Date : Wed, 06 Apr 2011 08:53:46 GMT+00:00
Gateway to College News: Giving the gift of love that stays with you - my.hsj.org Tweet this news
my.hsj.org--Antibiotics must be used to rid of Chlamydia. There are several prescriptions, but the most often prescribed are Zithromax and -Azithromycin-. But, as always, abstinence is the best policy to avoid any STD (sexually transmitted disease.)--- - Date : Thu, 07 Apr 2011 17:53:59 GMT+00:00
RPPR, CXTO and ISPH are the Stocks to Watch for April 6th from OTCPicks.com - Emailwire (press release) Tweet this news
Emailwire (press release)--Inspire's specialty eye care sales force generates revenue from the promotion of AZASITE® (-azithromycin- ophthalmic solution) 1% for bacterial conjunctivitis. Inspire receives royalties based on net sales of RESTASIS® (c - Date : Wed, 06 Apr 2011 13:19:24 GMT+00:00
CBI to file first charge sheet against Raja, others - Business Standard (blog) Tweet this news
Business Standard (blog)--Indian pharmaceutical companies producing macrolides such as erythromycin, roxithromy- cin, -azithromycin- and clarithromycin, used in treating infection of the upper respiratory tract, have reported a sharp rise in business afte - Date : Fri, 01 Apr 2011 19:30:50 GMT+00:00
Preoperative tear film optimization critical to surgical outcome - OSN SuperSite Tweet this news
OSN SuperSite--"Topical -azithromycin-, meibomian gland probing and other treatments for posterior blepharitis may also have a role prior to surgery in patients who do not respond to other forms of therapy," Dr. Tu said. Disclosure: Dr. - Date : Sat, 26 Mar 2011 02:10:54 GMT+00:00
InSite Vision announces positive phase I/II results for ISV-303 for reduction ... - pharmabiz.com Tweet this news
pharmabiz.com--The DuraSite platform is currently leveraged in two commercial products for the treatment of bacterial eye infections, AzaSite (-azithromycin- ophthalmic solution) 1% and Besivance (besifloxacin ophthalmic suspension) 0.6%. InSite vision is - Date : Fri, 25 Mar 2011 10:45:36 GMT+00:00
InSite Vision Announces Positive Phase 1/2 Results for ISV-303 for the ... - Business Wire (press release) Tweet this news
Business Wire (press release)--The DuraSite platform is currently leveraged in two commercial products for the treatment of bacterial eye infections, AzaSite ® (-azithromycin- ophthalmic solution) 1%, marketed in the US by Inspire Pharmaceuticals, and Be - Date : Tue, 22 Mar 2011 12:31:39 GMT+00:00

Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)

30S

Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)

30S
30S
subgroup |groupstyle=background:PowderBlue; |Aminoglycosides
(initiation inhibitors) |
Tetracycline antibiotics
(tRNA binding)
TetracyclinesDoxycycline# * Chlortetracycline * Clomocycline * Demeclocycline * Lymecycline * Meclocycline * Metacycline * Minocycline * Oxytetracycline * Penimepicycline * Rolitetracycline * Tetracycline
GlycylcyclinesTigecycline

Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)

30S
30S
subgroup |groupstyle=background:PowderBlue; |Aminoglycosides
(initiation inhibitors) |
Tetracycline antibiotics
(tRNA binding)
TetracyclinesDoxycycline# * Chlortetracycline * Clomocycline * Demeclocycline * Lymecycline * Meclocycline * Metacycline * Minocycline * Oxytetracycline * Penimepicycline * Rolitetracycline * Tetracycline
GlycylcyclinesTigecycline
30S
subgroup |groupstyle=background:PowderBlue; |Aminoglycosides
(initiation inhibitors) |
Tetracycline antibiotics
(tRNA binding)
TetracyclinesDoxycycline# * Chlortetracycline * Clomocycline * Demeclocycline * Lymecycline * Meclocycline * Metacycline * Minocycline * Oxytetracycline * Penimepicycline * Rolitetracycline * Tetracycline
GlycylcyclinesTigecycline
MLS (transpeptidation/translocation)
MacrolidesErythromycin# * Azithromycin# * Spiramycin * Midecamycin * Oleandomycin * Roxithromycin * Josamycin * Troleandomycin * Clarithromycin * Miocamycin * Rokitamycin * Dirithromycin * Flurithromycin * Ketolide (Telithromycin, Cethromycin)
LincosamidesClindamycin# * Lincomycin
StreptograminsPristinamycin * Quinupristin/dalfopristin * Virginiamycin



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