Vartan had a complicated club career. He started his career at Homenetmen Beirut, stayed there for four years and moved to Hekmeh FC. He spent two years there then moved back to Homenetmen. Then he went on a two-year loan to Al-Hekmé and returned to Homenetmen Beirut.
Vartan Ghazarian is the leading goal scorer in the history of the Lebanon national team with a record of 19 goals
(4 in World Cup qualifiers, 3 in Asian Cup qualifiers, 12 in friendlies).
On 16 November 2008, during Round 6 of the Lebanese Football League, at the age of 39 years, Vartan scored his 130th goal in the Lebanese first division against Tadamon Tyre, becoming officially the highest all-time scorer in the history of Lebanese football. Some officials do not recognize the 12 goals he scored in the 2000-2001 season which was canceled. However, his remaining recognized goals equal Fadi Alloush's total of 118 goals.
His first goal in the Lebanese league came on 23 January 1993 when he scored the second goal for Homentmen against Tadamon Tyre in the 54th minute.
Few years ago, he returned back to his original country, Armenia, where he currently lives.