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Prostacyclin analogues | Beraprost, Epoprostenol, Iloprost, Treprostinil | |
Endothelin receptor antagonists | Ambrisentan, Bosentan, Sitaxentan | |
PDE5 inhibitors | Sildenafil, Tadalafil | |
Statins--> | Simvastatin--> | |
Adjunctive therapy | Calcium channel blockers, Diuretics, Digoxin, Oxygen therapy, Warfarin |
PDE1 | MMPX * SCH-51866 * Vinpocetine | |
PDE2 | BAY 60-7550 * EHNA | |
PDE3 | Amrinone * Anagrelide * Bucladesine * Cilostamide * Cilostazol * Enoximone * KMUP-1 * Milrinone * Quazinone * RPL-554 * Siguazodan * Trequinsin * Vesnarinone * Zardaverine | |
PDE4 | Arofylline * Cilomilast * CP-80633 * Denbutylline * Drotaverine * Etazolate * Filaminast * Glaucine * HT-0712 * Ibudilast * ICI-63197 * Irsogladine * Mesembrine * Pentoxifylline * Propentofylline * Roflumilast * Rolipram * Ro20-1724 * RPL-554 * YM-976 | |
PDE5 | Acetildenafil * Avanafil * Dipyridamole * Icariin * Lodenafil * Mirodenafil * MY-5445 * Sildenafil * T-0156 * Tadalafil * Thiomethisosildenafil * Udenafil * Vardenafil | |
PDE6 | Zaprinast | |
PDE7 | BRL-50481 | |
PDE8 | ||
PDE9 | BAY 73-6691 * SCH-51866 | |
PDE10 | Papaverine * PF-2545920 * Tofisopam | |
PDE11 | ||
Nonselective | Caffeine * Theophylline * IBMX * Doxofylline | |
Unknown/ungrouped |