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Meloxicam

Meloxicam
Drug information
Systematic (IUPAC) name
IUPAC name4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide.
Chemical data
Mol. mass351.403 g/mol
Bioavailability89%
Protein binding99.4%
MetabolismHepatic (CYP2C9 and 3A4-mediated)
Half-life15 to 20 hours
ExcretionUrine and faeces equally
Therapeutic considerations
Pregnancy cat C(US) D in third trimester
RoutesOral

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Meloxicam is a nonsteroidal anti-inflammatory drug with analgesic and fever reducer effects. It is a derivative of oxicam, closely related to piroxicam, and falls in the enolic acid group of NSAIDs. It was developed by Boehringer-Ingelheim.


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