At the request of some middle-and West Jutland politicians airport, it was opened on 1 November 1965 when the first direct connection between Karup and Copenhagen was opened.
Airport ownership consisted of Viborg and Ringkjøbing county council districts and the municipalities of Herning, Holstebro, Viborg, Skive, Ikast, Karup, Struer, Ringkøbing, Lemvig and Skjern. It was agreed that Det Danske Luftfartsselskab - later SAS - would start flying on the route in exchange for a subsidy by the owners. In the beginning there was a single daily departures with a 15-passenger Heron aeroplane. The route was a success and there was no need for the subsidy. On the contrary, the airport's ongoing development was paid for with the operating income and no additional public support aside from the owners' initial deposits.
Today, the airport has up to 14 daily flights and approximately 200,000 passengers annually. The airport is operated today by Norwegian, Cimber Sterling and several national and international taxi-flight companies.
In 1968 the airport's first terminal was built. Until then, it had rented premises at the airbase. In 1991 the present terminal, Glass House on the Heath designed by Architect Firm Torsten Riis Andersen, was inaugurated.
Lemvig and Skjern municipality sold their shares to Karup council (now Viborg council) in 2002.
As of 1st. January 2007 the owners are Herning, Holstebro, Ikast-Brande, Lemvig, Ringkobing-Skjern, Silkeborg, Skive, Struer and Viborg counties.