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Fluconazole

Drug information
Systematic (IUPAC) name
IUPAC name2-(2,4-difluorophenyl)-
1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
Chemical data
Mol. mass306.271 g/mol
Bioavailability>90%
Protein binding11 � 12%
MetabolismHepatic 11%
Half-life30 hours (range 20-50 hours)
ExcretionRenal 61 � 88%
Therapeutic considerations
Pregnancy cat D (Au), C (U.S.)
Legal status S3/S4 (Au), POM (UK), ℞-only (U.S.)
RoutesOral, IV, topical

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Fluconazole (c-eniconfluːˈkɒnəzoʊl) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. In a bulk powder form, it appears as a white crystalline powder, and it is very slightly soluble in water and soluble in alcohol. It is commonly marketed under the trade name Diflucan or Trican (Pfizer). In Mexico it is sold over the counter as Alfumet, Afungil or Dofil. It is marketed under the brand name Candivast in the Persian Gulf area.

Fluconazole Video

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0.75 min. | 0 user rating		 Oral candidiasis or the oral thrush is the infection of candida in oral mucosa, this should be treated with antifungal like nystatin or fluconazole. You should not give any antibiotics, however you can add vitamin B. Oral thrush is seen in immunocompromised candidates like in HIV or may be seen with diabetes or Tuberculosis.
0.63 min. | 0 user rating		 Hi, my name is Gwen and I live in Los Angeles and I am going to review my most recent with PharmacyEscrow.com. First, I want to say I give this order a rating of 5 stars. This is probably the fifth time that I have ordered through PharmacyEscrow.com and I placed two drug orders this time that I was ordering. One was for Fluconazole or Diflucan as it is known in the US, 20 tablets of 100 MG each and I believe that came from the Indian pharmacy and then, the second thing I have ordered was 2000 International Units, well, 3 bottles of 2000 International Units each of UNI HCG and I believe that came from Singapore pharmacy. Now, overall, like I said I give it a 5. The delivery was super speedy this time. I paid for normal delivery but it came within a week. I think I placed my order on April 26th and everything, since they were coming from two pharmacies; they came a day apart but around May 7th. So, a week and a day later, pretty much. It was awesome. This was the first, the one negative thing that I would say about this order. It's the first time I had to do the medical review from the pharmacist or from the doctor and I had to pay $4.99 USD for that and I've never had to do that before with any of my orders which, you know, is not that bad. It's only $5 USD which is nothing compared to actually going to see a doctor here in the US with or without insurance. So, it's not that big deal but it was kind of surprise and I will be upset if, you know, I go to order in the future <b>...</b>
4.92 min. | 5.0 user rating		 Animal prescription medications are available through Drs. Foster and Smith's Free-Shipping Pharmacy at prices lower than your vet for the exact same product. We'll call to get the prescription for you, and ship it out FREE. Drs. Foster and Smith Inc. is fully licensed in all 50 states. This medication can be ordered at www.drsfostersmith.com
1.57 min. | 0 user rating		 Hi, my name is Gwen and this is my video review for my most recent order from PharmacyEscrow.com. This is I think my sixth or seventh or maybe even eighth order that I've placed. I've always been super happy. Once again I'm a happy customer, I ordered two things this time both were Diflucan or Fluconazole, I ordered 20 tablets of 100mg each, generic from the Indian Pharmacy as well as 3 tablets of the 200mg also generic, also from the Indian pharmacy and once again, my order came super fast, I only need, always pay for the regular shipping and it comes within a week of actually placing my order, so that's awesome and I'm located in Los Angeles by the way, and ya, I was also very happy with the products that i got, I think I prefer the 100mg over the 200mg. The 100mg come in little foil packets and it's a little dissolvable pink tablet that you know, you dissolve in a tablespoon of purified water and it actually tastes really good, it tastes kind of sweet, so, it's like a nice little I'm taking my medicine treat. The 200mgs are just a swallow able tablet, they do have a little groove in the middle where you can cut them in half which I did. All around I was very pleased, I can really feel the potency of these anti fungal medications, you can really feel it coursing through your body and you know, really getting rid of whatever fungal infection, I've been using them to treat a Candida infection and they are working great, the only thing that I do say is they work so great <b>...</b>
2.22 min. | 0 user rating
Arthritis just keeps improving, even off the humira! Diflucan/fluconazole seems to have worked. Mum has been diagnosed with Lyme by Igenex test.
9.27 min. | 0 user rating		 betapacerecipe.cx.cc - fluconazole yeast infection medicine
0.17 min. | 0 user rating		 tinyurl.com Buy Diflucan Online At The Cheapest Prices From A Reliable Pharmacy And Get The Fastest Delivery And The Best Prices Online.
0.52 min. | 0 user rating
5.82 min. | 0 user rating		 also see my Lyme blog: freeideasblog.blogspot.com
4.62 min. | 0 user rating

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MethylGene Reports Clinical Data for MGCD265 at the 2011 American Society of ... - Marketwire (press release) Tweet this news
Marketwire (press release)--The Company's lead product candidates include: MGCD265, an oral Met/VEGF receptor kinase inhibitor that is in Phase 1/2 clinical trials for solid tumor cancers and MGCD290, a fungal Hos2 inhibitor, for use in combination w - Date : Fri, 03 Jun 2011 12:02:01 GMT+00:00
MethylGene Closing Private Placement - PR-USA.net (press release) Tweet this news
PR-USA.net (press release)--The Company's lead product candidates include: MGCD265, an oral multi-targeted kinase inhibitor that is in Phase 1/2 clinical trials for solid tumor cancers and MGCD290, a fungal Hos2 inhibitor, for use in combination with - Date : Sun, 03 Apr 2011 06:20:11 GMT+00:00
MethylGene Reports Fourth Quarter and Full Year 2010 Financial Results - SYS-CON Media (press release) Tweet this news
SYS-CON Media (press release)--The Company's lead product candidates include: MGCD265, an oral Met/VEGF receptor kinase inhibitor that is in Phase 1/2 clinical trials for solid tumor cancers and MGCD290, a fungal Hos2 inhibitor, for use in combinatio - Date : Wed, 30 Mar 2011 11:36:36 GMT+00:00
MethylGene Reports Fourth Quarter and Full Year 2010 Financial Results - PR-USA.net (press release) Tweet this news
PR-USA.net (press release)--The Company's lead product candidates include: MGCD265, an oral Met/VEGF receptor kinase inhibitor that is in Phase 1/2 clinical trials for solid tumor cancers and MGCD290, a fungal Hos2 inhibitor, for use in combination w - Date : Thu, 31 Mar 2011 12:35:37 GMT+00:00
Overgrowth of yeast causes host of issues - Wilkes Barre Times-Leader Tweet this news
Wilkes Barre Times-Leader--To kill off an existing candida overgrowth, he uses prescription medications, such as -fluconazole-, an antifungal, and natural remedies such as castor bean oil extract and caprylic acid. Crooker used some of those remedies. ... - Date : Tue, 29 Mar 2011 05:25:29 GMT+00:00
MethylGene to Present MGCD265 Data at the American Association for Cancer ... - Marketwire (press release) Tweet this news
Marketwire (press release)--The Company's lead product candidates include: MGCD265, an oral Met/VEGF receptor kinase inhibitor that is in Phase 1/2 clinical trials for solid tumor cancers and MGCD290, a fungal Hos2 inhibitor, for use in combination w - Date : Tue, 29 Mar 2011 11:32:56 GMT+00:00
MethylGene Announces $34.5 Million Financing to Develop Oncology & Antifungal ... - BioMedReports (subscription) Tweet this news
BioMedReports (subscription)--The proceeds of the financing will also be used to fund Phase 2 studies with MGCD290+-fluconazole- in vulvovaginal candidiasis (VVC) which is caused by the Candida fungus. Antifungal drugs, particularly the family of drugs ca - Date : Thu, 24 Mar 2011 22:07:52 GMT+00:00
Prevalence of invasive fungal disease in hematological patients at a tertiary ... - 7thSpace Interactive (press release) Tweet this news
7thSpace Interactive (press release)---Fluconazole- prophylaxis had been provided for 28 out of the 39 (71.8%) cases, while 4 (10.3%) were on itraconazole prophylaxis. The in-hospital mortality was 28.2% (11 of 39 cases), of which 5 (12.8%) deaths were at - Date : Mon, 28 Feb 2011 16:05:37 GMT+00:00
ATS issues statement on the treatment of pulmonary fungal infections - EurekAlert (press release) Tweet this news
EurekAlert (press release)---...- itraconazole and -fluconazole-, the guidelines include recommendations for use of newer agents, including extended-spectrum triazoles and echinocandins, ... - Date : Mon, 03 Jan 2011 19:27:08 GMT+00:00
MethylGene Presents Favorable Clinical Data for Mocetinostat at the 52nd ... - PR-CANADA.net (press release) Tweet this news
PR-CANADA.net (press release)---...- MGCD290, a fungal Hos2 inhibitor for use in combination with -fluconazole- for fungal infections which has completed Phase 1 clinical studies; ... - Date : Wed, 08 Dec 2010 09:21:04 GMT+00:00

Antifungals (D01 and J02)

Wall/
membrane

Antifungals (D01 and J02)

Wall/
membrane
Wall/
membrane
subgroup

Antifungals (D01 and J02)

Wall/
membrane
Wall/
membrane
subgroup
Wall/
membrane
subgroup |groupstyle=background:PowderBlue; |Ergosterol
inhibitors |
Polyene antimycotics
(ergosterol binding)
topical: (Natamycin, Nystatin#)
systemic: (Amphotericin B#)
Allylamines
(squalene monooxygenase
inhibitors)
topical: (Amorolfine, Butenafine, Naftifine, Terbinafine)
systemic: (Terbinafine)



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