He has 5 brothers and 1 sister. His older brother Michael is also an actor.
Spears has been in the spotlight since age 10 starting with his first role in TNT's production of Geronimo. It was shot in Arizona.
According to him, his most rewarding role to date was Shane Chasing Horse in Dreamkeeper.
When he was cast for the lead in Black Cloud (2004), directed by Rick Schroder, he trained for three months with legendary boxing trainer Jimmy Gambia to perfect his boxing skills before filming started. The story is about a Navajo boxer training for the Golden Gloves with the promise of a spot at the Olympics while struggling with the secrets of his family's heritage. One of the scenes was filmed in Las Vegas during the 2003 Golden Gloves National Championship.
He attended and was a mentor at the 2nd annual HatcH audiovisual festival in Bozeman, Montana in October 2005. HatcH is a film and arts festival whose mission is to provide mentorship, education, inspiration, and recognition to the next generation of creative innovators.
He can speak Lakota, but has admitted that he is not fluent. He is an avid outdoorsman with hunting, fishing, archery and rodeo experience. Eddie can dance both the traditional and grass ceremonies of the Lakota. He also travels nationally as a keynote speaker.