Crohns disease

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Crohn's disease, also known as inflammatory bowel disease, regional enteritis, and Granulomatous ileocolitis disease is an inflammatory disease of the intestines that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea (which may be bloody if inflammation is at its worst), vomiting, or weight loss, but may also cause complications outside of the gastrointestinal tract such as skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration.

Crohn's disease is thought to be an autoimmune disease, in which the body's immune system attacks the gastrointestinal tract, causing inflammation; it is classified as a type of inflammatory bowel disease. There has been evidence of a genetic link to Crohn's disease, putting individuals with siblings afflicted with the disease at higher risk. It is understood to have a large environmental component as evidenced by the higher number of cases in western industrialized nations. Males and females are equally affected. Smokers are two times more likely to develop Crohn's disease. Crohn's disease affects between 400,000 and 600,000 people in North America. Prevalence estimates for Northern Europe have ranged from 27 � 48 per 100,000. Crohn's disease tends to present initially in the teens and twenties, with another peak incidence in the fifties to seventies, although the disease can occur at any age.

There is no known pharmaceutical or surgical cure for Crohn's disease. Treatment options are restricted to controlling symptoms, maintaining remission, and preventing relapse.

The disease was named for American gastroenterologist Burrill Bernard Crohn, who, in 1932, along with two colleagues, described a series of patients with inflammation of the terminal ileum, the area most commonly affected by the illness. For this reason, the disease has also been called regional ileitis or regional enteritis. The condition, however, has been independently identified by others in the literature prior, the most notable one being in 1904 by Polish surgeon Antoni Leśniowski for whom the condition is additionally named (Leśniowski-Crohn's disease) in the Polish literature.

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High Stress of Crohn's Disease Associated With Flare-Ups - Doctors Lounge Doctors Lounge--Posttraumatic stress disorder associated with the burden of having -Crohn's disease- appears to be linked to disease exacerbations, according to a study ... - Date : Fri, 03 Dec 2010 00:19:28 GMT+00:00
JNM: Low-dose FDG PET/CT enterography improves assessment in Crohn's - Health Imaging & IT Health Imaging & IT--Thirteen patients with -Crohn's disease- were prospectively enrolled in the pilot study and underwent abdominal-pelvic PET/CTE using neutral oral and ... - Date : Wed, 01 Dec 2010 16:00:50 GMT+00:00
American Academy of Pediatrics Reviews Use of Probiotics, Prebiotics - Medscape Medscape--Before probiotics can be recommended for treatment of irritable bowel syndrome, -Crohn's disease-, colic, and constipation, or for prevention of common ... - Date : Thu, 02 Dec 2010 18:00:41 GMT+00:00
Food Components Influence Bacterial Pathology of Crohn's Disease - Medscape Medscape--August 27, 2010 � The translocation of Escherichia coli across M (microfold) cells and Peyer's patches in -Crohn's disease- is inhibited by plant fiber but ... - Date : Fri, 27 Aug 2010 19:57:07 GMT+00:00
Inflammatory bowel disease linked to antibiotic treatment for acne - Examiner.com Examiner.com--The overall incidence of bowel disease was rare, but still showed some correlation with the use of the antibiotics. Patients with -Crohn's disease- showed a ... - Date : Thu, 26 Aug 2010 03:08:18 GMT+00:00
Curing Crohn's: One Shake At A Time - KMGH Denver KMGH Denver--That's life for people with -Crohn's disease-, a chronic condition that attacks the body's digestive tract. Now, some folks are turning away from traditional ... - Date : Fri, 27 Aug 2010 20:15:55 GMT+00:00
Inflammatory Bowel Disease: News on Diet Therapy - EmpowHer (blog) EmpowHer (blog)--Diet therapy can reduce the need for drugs and surgery in -Crohn's disease- and ulcerative colitis, the two most common forms of inflammatory ... - Date : Thu, 26 Aug 2010 16:52:31 GMT+00:00
Reportlinker Adds Commercial Insight: Inflammatory Bowel Disease Future market ... - PR Newswire (press release) PR Newswire (press release)---...- combined with the impending impact from the seminal SONIC study, which will result in -Crohn's disease- patients receiving biologics in combination with ... - Date : Wed, 25 Aug 2010 12:03:51 GMT+00:00
Using Humira to treat Crohn's disease - Helium Helium---Crohn's disease- is a type of inflammatory bowel disease that causes abdominal pain and uncontrollable diarrhea that, ... - Date : Wed, 25 Aug 2010 12:08:44 GMT+00:00
Accutane Lawsuits Reach 5000 Cases Filed - Drug Alert Drug Alert--Accutane users have complained of side effects including inflammatory bowel disease (IBD), -Crohn's Disease- and ulcerative colitis, all which are ... - Date : Wed, 21 Jul 2010 17:41:53 GMT+00:00

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High Stress of Crohn's Disease Associated With Flare-Ups - Doctors Lounge

Doctors Lounge--Posttraumatic stress disorder associated with the burden of having -Crohn's disease- appears to be linked to disease exacerbations, according to a study ... - Date : Fri, 03 Dec 2010 00:19:28 GMT+00:00

JNM: Low-dose FDG PET/CT enterography improves assessment in Crohn's - Health Imaging & IT

Health Imaging & IT--Thirteen patients with -Crohn's disease- were prospectively enrolled in the pilot study and underwent abdominal-pelvic PET/CTE using neutral oral and ... - Date : Wed, 01 Dec 2010 16:00:50 GMT+00:00

American Academy of Pediatrics Reviews Use of Probiotics, Prebiotics - Medscape

Medscape--Before probiotics can be recommended for treatment of irritable bowel syndrome, -Crohn's disease-, colic, and constipation, or for prevention of common ... - Date : Thu, 02 Dec 2010 18:00:41 GMT+00:00

Food Components Influence Bacterial Pathology of Crohn's Disease - Medscape

Medscape--August 27, 2010 � The translocation of Escherichia coli across M (microfold) cells and Peyer's patches in -Crohn's disease- is inhibited by plant fiber but ... - Date : Fri, 27 Aug 2010 19:57:07 GMT+00:00

Inflammatory bowel disease linked to antibiotic treatment for acne - Examiner.com

Examiner.com--The overall incidence of bowel disease was rare, but still showed some correlation with the use of the antibiotics. Patients with -Crohn's disease- showed a ... - Date : Thu, 26 Aug 2010 03:08:18 GMT+00:00

Curing Crohn's: One Shake At A Time - KMGH Denver

KMGH Denver--That's life for people with -Crohn's disease-, a chronic condition that attacks the body's digestive tract. Now, some folks are turning away from traditional ... - Date : Fri, 27 Aug 2010 20:15:55 GMT+00:00

Inflammatory Bowel Disease: News on Diet Therapy - EmpowHer (blog)

EmpowHer (blog)--Diet therapy can reduce the need for drugs and surgery in -Crohn's disease- and ulcerative colitis, the two most common forms of inflammatory ... - Date : Thu, 26 Aug 2010 16:52:31 GMT+00:00

Reportlinker Adds Commercial Insight: Inflammatory Bowel Disease Future market ... - PR Newswire (press release)

PR Newswire (press release)---...- combined with the impending impact from the seminal SONIC study, which will result in -Crohn's disease- patients receiving biologics in combination with ... - Date : Wed, 25 Aug 2010 12:03:51 GMT+00:00

Using Humira to treat Crohn's disease - Helium

Helium---Crohn's disease- is a type of inflammatory bowel disease that causes abdominal pain and uncontrollable diarrhea that, ... - Date : Wed, 25 Aug 2010 12:08:44 GMT+00:00

Accutane Lawsuits Reach 5000 Cases Filed - Drug Alert

Drug Alert--Accutane users have complained of side effects including inflammatory bowel disease (IBD), -Crohn's Disease- and ulcerative colitis, all which are ... - Date : Wed, 21 Jul 2010 17:41:53 GMT+00:00

Crohn's disease

Main		Inflammatory bowel disease * Biological therapy for inflammatory bowel disease * Treatment of Crohn's disease * Crohn's Disease Activity Index
Anatomical terms		Abdominal pain * Anal abscess * Erythema nodosum * Fistula * Granuloma * Ileum * Ileitis * Malabsorption * Proctitis * Protein losing enteropathy * Pyoderma gangrenosum * Sacroiliitis * Short bowel syndrome * Small bowel obstruction * Stenosis
History		Giovanni Battista Morgagni * Burrill Bernard Crohn
Organizations		Crohn's and Colitis Foundation of America * National Society for Colitis and Crohn's Disease * The Crohn's and Colitis Foundation of Canada
People		List of people diagnosed with Crohn's disease * Deaths from Crohn's disease